ReviewCureus2025
From Glycemia to Grip: A Comprehensive Review of Musculoskeletal Complications in Diabetic Patients.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Missed Autoimmune Diabetes: Latent Autoimmune Diabetes in Adults in the Setting of Autoimmune Clustering.Cureus · 2026Article
- Genetics and pathophysiology of diffuse idiopathic skeletal hyperostosis.Frontiers in endocrinology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is a chronic metabolic disorder with well-established vascular complications. Its impact on the musculoskeletal (MSK) system is often underrecognized in clinical practice. MSK disorders contribute significantly to pain, functional limitations, and decreased quality of life in individuals with diabetes. However, they remain inadequately addressed in primary care settings. This narrative review aims to synthesize current evidence on the prevalence, assessment, pathophysiology, clinical features, and management of MSK complications in individuals with diabetes, with an emphasis on the role of primary care providers (PCPs) in early detection and management. A comprehensive literature search was conducted using PubMed, Google Scholar, and Scopus to identify peer-reviewed studies published between 2000 and 2025. Findings were organized thematically. MSK complications, including diabetic cheiroarthropathy, trigger finger, adhesive capsulitis, carpal tunnel syndrome (CTS), diffuse idiopathic skeletal hyperostosis (DISH), and Charcot joint, are significantly more prevalent in diabetic populations compared to non-diabetics. These conditions are driven by hyperglycemia-induced biochemical changes, chronic inflammation, and microvascular dysfunction. Primary care interventions encompass lifestyle modification, physical therapy, and pharmacologic management. These can help mitigate disability and improve patient outcomes. Despite the burden, diabetes-related MSK disorders are often overlooked due to time constraints, lack of awareness, and absence of standardized guidelines. Integrating MSK assessment into routine diabetes care is essential to reduce morbidity and preserve mobility in individuals with diabetes. PCPs play a central role in early identification and management of these conditions. Patient education, multidisciplinary collaboration, and future development of evidence-based screening protocols are critical in improving management of diabetes-related MSK complications.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.