Evidence map›Paper›PMID 40995243›Full record

ArticleCureus2025

Retreatment of a Tooth With Calcified Canals Using Cold Ceramic: A Case Report.

Jalil Modaresi, Mojtaba Mehrabanian, Rita Marincsák, Mina Afshar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jalil ModaresiEndodontics, Shahid Sadoughi University of Medical Sciences, Yazd, IRN.
Mojtaba MehrabanianDentistry, Bupa Dental Care, Dingwall, GBR.
Rita MarincsákOperative Dentistry and Endodontics, University of Debrecen, Debrecen, HUN.
Mina AfsharSchool of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, IRN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Root canal treatment (RCT) has high success rates; however, failures may occur when chemo-mechanical preparation or obturation are inadequate, leading to persistent infection and periapical lesions. Calcification of the root canal system may obstruct effective canal negotiation and preparation, increasing the risk of under-debridement and treatment failure. When calcified canals cannot be fully managed, the prognosis is typically poor, necessitating extraction or apical surgery. This case report presents nonsurgical retreatment of a symptomatic mandibular left first molar with partially calcified canals. Despite careful negotiation, apical patency could not be safely achieved. Chemo-mechanical debridement with copious irrigations was performed, and the canals were obturated with cold ceramic (CC), a hydraulic calcium silicate-based cement, to establish a corono-apical seal. Symptoms resolved, and radiographs showed near-complete periapical healing maintained at four years. Within the limits of a single case, the favorable outcome is most likely to reflect effective disinfection combined with a secure seal. CC was selected for its biocompatibility, alkaline pH-associated antibacterial effect, and sealing capacity, and it may serve as a pragmatic obturation alternative to gutta-percha when full-length instrumentation is not feasible. A conservative, tooth-preserving approach can be appropriate in similar calcified cases. Further studies are needed to explore CC's potential and long-term outcomes.

Indexed as

calcificationchemo-mechanical preparationcold ceramicnonsurgical retreatmentperiapical lesion

Identifiers

PMID40995243
PMCPMC12455265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.