ArticleCureus2025
Antisynthetase Syndrome Masquerading As Psoriasis and Psoriatic Arthritis: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Antisynthetase syndrome (ASyS) is a subtype of idiopathic inflammatory myopathy. It may have cutaneous findings like psoriasis and dermatomyositis, making clinical diagnosis challenging. We report a case of a 49-year-old woman who presented with initial symptoms of psoriasis and psoriatic arthritis: scaly patches on the scalp, scaly patches on the elbows, hyperkeratotic scaly plaques on her palms, and inflammatory joint symptoms. However, the development of phototherapy-induced flares and resistance to topical steroids prompted reconsideration of her diagnosis. Further investigations revealed the presence of anti-Jo-1 antibodies, which led to the diagnosis of ASyS. This case emphasizes the need for a broad differential diagnosis when evaluating psoriasiform skin changes, particularly in cases with atypical features or resistance to standard treatments.
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