Evidence map›Paper›PMID 40995178›Full record

ArticleFrontiers in nutrition2025

Optimization and purification of natural protein extract from hazelnut press cake and its antioxidant activity.

Yuan Fang, Jiajie Li, Xuyao Zhu, Xinru Li, Songzhe Xu, Hao Wu, Huifeng Zhang, Yanan Luo

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuan FangSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Jiajie LiSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Xuyao ZhuSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Xinru LiSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Songzhe XuSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Hao WuSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Huifeng ZhangSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.
Yanan LuoSchool of Laboratory Medicine (Pharmaceutical Sciences), Jilin Medical University, Jilin City, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to enhance the basic criteria for protein extraction from hazelnuts via the response surface technique and to explore the antioxidant characteristics of the isolated hazelnut protein. The purified hazelnut protein with high quality was obtained using the ÄKTA pure system through a HiTrap DEAE FF column. The refined parameters for extraction included: an extraction duration of 2 h, a temperature set at 33 °C, a liquid-to-solid ratio 8:1, and a 2.32 g protein extraction yield/50 g hazelnut press cake. The crude hazelnut protein was identified by LC-MS, which primarily included 41 proteins (only 10 shown). Antioxidant-activity investigations revealed that purified hazelnut protein had high scavenging activity of DPPH radicals. Furthermore, H

Indexed as

antioxidant activityhazelnutnatural proteinoptimizationpurification

Identifiers

PMID40995178
PMCPMC12455074

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.