Evidence map›Paper›PMID 40995132›Full record

ArticleSurgery open science2025

Association of frailty with perioperative outcomes after mastectomy with and without immediate breast reconstruction.

Gizem Bilgili, Sara Sakowitz, Konmal Ali, Dariush Yalzadeh, Barzin Badiee, Melissa Justo, Mediget Teshome, Edward Nahabet, Peyman Benharash

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgery open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gizem BilgiliDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Sara SakowitzDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Konmal AliDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Dariush YalzadehDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Barzin BadieeDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Melissa JustoDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Mediget TeshomeDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Edward NahabetDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.
Peyman BenharashDepartment of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Frailty has been recognized as an independent risk factor for adverse postoperative outcomes. Coding based frailty instruments such as the Modified Frailty Index (mFI-5) are increasingly incorporated into risk models to provide better prediction of mortality, and complications. However, few have examined the large-scale utility of mFI-5 in the context of mastectomy and breast reconstruction. Methods: All elective adult (≥ 18 years) hospitalizations in women for mastectomy, with and without immediate breast reconstruction (IBR) were identified in the 2016-2022 National Inpatient Sample. Patients with an mFI-5 score ≥ 2 were considered Frail. Multivariable regression models were constructed to evaluate the association of frailty with major complications, length of stay (LOS) and inpatient costs. Results: Of an estimated 150,215 patients, 14 % were considered Conclusions: Frailty remains associated with greater postoperative complications and length of stay. Status of frailty as ascertained by the mFI-5 may be useful in stratifying patient risk among those receiving mastectomy.

Indexed as

breast cancerbreast reconstructionFrailtymastectomymFI-5Modified Frailty Index

Identifiers

PMID40995132
PMCPMC12455203

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.