ArticleIntegrative medicine research2026
Pharmacopuncture for patients with psychological stress caused by traffic accidents: A pragmatic randomized controlled pilot trial.
Article in Integrative medicine research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06107777 (The Efficacy of Pharmacopuncture on Inpatients With Psychological Stress Caused by Traffic Accidents), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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The Efficacy of Pharmacopuncture on Inpatients With Psychological Stress Caused by Traffic Accidents: A Practical Randomized Control Pilot Study
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14 authors.
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Abstract
Background: The effectiveness and safety of stress-focused pharmacopuncture in patients experiencing psychological stress following a traffic accident remain unclear. We aimed to conduct a randomized controlled trial to determine the effectiveness and safety of pharmacopuncture for these patients. Methods: A total of 50 patients were included in this randomized controlled pilot trial. Inpatients who scored ≥8 on the Hospital Anxiety and Depression Scale-Anxiety (HADS-A) or Depression (HADS-D) subscales following a traffic accident were randomized to receive either integrative Korean medicine (IKM) treatment alone (comparison group) or IKM treatment combined with stress-focused pharmacopuncture (pharmacopuncture group). The primary outcomes were the changes in the Hospital Anxiety and Depression Scale (HADS) scores, HADS total score (HADS-T), HADS-A, and HADS-D, from baseline to discharge. Secondary outcomes included the Numeric Rating Scale (NRS) for anxiety, depression, and physical pain; the Korean version of the Impact of Event Scale-Revised (IES-R-K); the Korean version of the Insomnia Severity Index (ISI-K); the EuroQol 5-Dimension (EQ-5D); and the Patient Global Impression of Change (PGIC) score. Results: Compared to the comparison group, the pharmacopuncture group showed statistically significant improvements in the HADS-T (difference: 2.30, 95 % CI 0.53 to 4.07), HADS-A (difference: 1.09, 95 % CI 0.17 to 2.02), HADS-D (difference: 1.25, 95 % CI 0.25 to 2.25), NRS of anxiety (difference: 0.85, 95 % CI 0.10 to 1.59), and PGIC (difference: 0.52, 95 % CI 0.07 to 0.97) at the primary endpoint. No serious adverse events were reported. Conclusion: Stress-focused pharmacopuncture may alleviate anxiety and depression symptoms and potentially accelerate recovery after traffic accidents. Trial registration: ClinicalTrials.gov, NCT06107777.
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