Evidence map›Paper›PMID 40995037›Full record

ReviewJournal of rheumatic diseases2025

Association between serum urate, gout and chronic kidney disease: a scoping review of systematic reviews and meta-analyses.

Yoon-Jeong Oh, Jung-Min Shin, Jin-Wuk Hur, Chang-Nam Son

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of rheumatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yoon-Jeong Oh *Eulji Rheumatology Research Institute, Eulji University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1028-3481
Jung-Min Shin *Eulji Rheumatology Research Institute, Eulji University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7916-3002
Jin-Wuk HurEulji Rheumatology Research Institute, Eulji University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8211-2951
Chang-Nam SonEulji Rheumatology Research Institute, Eulji University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1722-2190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperuricemia is highly prevalent in patients with chronic kidney disease (CKD) due to reduced renal urate clearance, which leads to an increased incidence of gout in this population. Additionally, hyperuricemia may be associated with the progression of CKD. Hyperuricemia, gout, and CKD are closely interconnected; however, high-quality evidence to guide the management of hyperuricemia and gout in CKD patients remains insufficient. This literature review aimed to describe the association between hyperuricemia, gout, and CKD. This study reviewed 26 meta-analyses on the relationship between gout, serum urate levels, and CKD and was performed following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement and guidelines. This study demonstrated that the hyperuricemia and gout is associated with high risk of incident CKD. In addition, hyperuricemia is a significant risk factor for CKD progression. However, the renoprotective effects of different types of urate lowering therapy showed inconsistent results. These review findings may contribute to the improvement of the management of CKD patients with hyperuricemia or gout.

Indexed as

Chronic kidney diseaseGoutMeta-analysisUrate

Identifiers

PMID40995037
PMCPMC12455028

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.