Evidence map›Paper›PMID 40994959›Full record

ReviewFrontiers in oncology2025

The use of granulocyte colony-stimulating factors in the management of breast cancer patients.

Anna Bałata, Ewa Szombara, Zbigniew I Nowecki, Katarzyna Pogoda

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna BałataDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Ewa SzombaraDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Zbigniew I NoweckiDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Katarzyna PogodaDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamic development of oncology poses new challenges to health care practitioners (HCPs), related to the introduction of modern targeted therapies, immunotherapies, or new chemotherapy regimens. The previous treatment algorithm for neutropenia and febrile neutropenia have significantly reduced the frequency of these complications in long-term therapies. Currently, breast cancer (BC) treatment is also based on the use of modern therapies, showing different toxicity profile. This article discusses the role of granulocyte colony-stimulating factors (G-CSFs) in well-known and new therapies used in the treatment of breast cancer patients. The factors influencing the development of hematological complications such as neutropenia and febrile neutropenia were presented. An important aspect of the assessment of patients at increased risk of therapy-induced toxicity was discussed with highlighting the fact that the treatment regimen is not the only factor influencing the development of adverse events (AEs). The aim of the study is to consolidate recommendations for the primary and secondary prevention of neutropenia and febrile neutropenia and related improvement of treatment outcomes in patients with BC.

Indexed as

anticancer therapy toxicitybreast cancerfebrile neutropeniafilgrastimgranulocyte colony-stimulating factorsneutropeniapegfilgrastim

Identifiers

PMID40994959
PMCPMC12454048

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.