Evidence map›Paper›PMID 40994913›Full record

ArticleFrontiers in cardiovascular medicine2025

Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.

Yuko Horikoshi, Rie Sakuraba-Hirata, Nina Suzuki, Yuki Inomata, Moe Oikawa, Toa Kotani, Takumu Watanabe, Eri Takahashi, Kanako Okazaki, Masayuki Hoshi and 11 more

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

21 authors.

Yuko Horikoshi *Department of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Rie Sakuraba-HirataDepartment of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Nina SuzukiDepartment of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Yuki InomataDepartment of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Moe OikawaDepartment of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Toa KotaniDepartment of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Takumu WatanabeDepartment of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Eri TakahashiDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Kanako OkazakiDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Masayuki HoshiDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Yasuhiro EndoDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Tatsuya NakanowatariDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Hiroaki AbeDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Yasuaki KusumotoDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Mieko YokozukaDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Yoshitaka ShibaDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Yoshinobu TanakaDepartment of Occupational Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Akihiko AsaoDepartment of Occupational Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Shigeki KurasawaDepartment of Occupational Therapy, Fukushima Medical University School of Health Sciences, Fukushima, Japan.
Yasuchika TakeishiDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
Akiomi Yoshihisa *Department of Clinical Laboratory Sciences, Fukushima Medical University School of Health Sciences, Fukushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Cardio-ankle vascular index (CAVI) is a non-invasive method for evaluating arterial stiffness. In adults, CAVI has been reported to show negative correlation with body mass index (BMI) known as the "obesity paradox"; however, whether this also applies to children remains unclear. In addition, childhood obesity is a problem in developed countries, and the utility of CAVI in children has not yet been clarified. We here aimed to clarify the relationship between obesity parameters and CAVI in healthy children. Methods: This was a cross-sectional study conducted in 2024. We evaluated CAVI and its associated factors in 590 children aged 6-15 years (mean age: 10.5 years, 51.0% female). Additionally, obesity parameters, including the Rohrer index, percentage of overweight (POW), body fat percentage and body fat mass determined by bioelectrical impedance analysis, and BMI were assessed. The participants were categorized into groups based on the obesity parameters. Results: CAVI decreased as obesity level increased, showing the lowest CAVI in the highest obesity category. CAVI was positively correlated with age ( Conclusion: Obesity parameters are negatively and independently associated with CAVI in healthy children.

Indexed as

body fat percentagebody mass indexcardio-ankle vascular indexobesity paradoxpercentage of overweightRohrer index

Identifiers

PMID40994913
PMCPMC12454398

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