Evidence map›Paper›PMID 40994902›Full record

Trial reportDrug design, development and therapy2025

Lidocaine-Based vs Sufentanil-Based PCIA After Pulmonary Resection Surgery: A Randomized Controlled Trial.

Bin Tian, Yumin Wu, Wenjie Zhang, Ruijuan Liu, Song Qu, Zhenying Zhang, Wenjun Yan

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bin Tian *Department of Anesthesiology, Gansu Provincial Hospital, Lanzhou, People's Republic of China.
Yumin Wu *Department of Anesthesiology, Nanzhang People's Hospital, Xiangyang, People's Republic of China.
Wenjie ZhangDepartment of Anesthesiology, Affiliated Hospital of Shandong Second Medical University, Weifang, People's Republic of China.
Ruijuan LiuDepartment of Anesthesiology, Gansu Provincial Hospital, Lanzhou, People's Republic of China.
Song QuDepartment of Anesthesiology, Guian Hospital The Affiliated Hospital of Guizhou Medical University, GuiYang, People's Republic of China.
Zhenying ZhangDepartment of Anesthesiology, Gansu Provincial Hospital, Lanzhou, People's Republic of China.ORCID 0009-0000-3765-0830
Wenjun YanDepartment of Anesthesiology, Gansu Provincial Hospital, Lanzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We investigated the efficacy and safety of lidocaine-based patient-controlled intravenous analgesia (PCIA), compared with sufentanil-based PCIA on postoperative pain and recovery quality in patients undergoing thoracoscopic lung surgery. Methods: We recruited 160 patients undergoing thoracoscopic lung surgery who were randomized to receive lidocaine-based PCIA (1.5 mg/kg/h) or sufentanil-based PCIA (2 μg/mL) within 48 hours postoperatively. The primary endpoint was visual analogue scores (VAS) pain scores at 6, 12, 24, and 48 hours postoperatively. Postoperative quality of recovery-15 (QoR-15) scores and other prespecified endpoints were also recorded. Results: VAS pain scores at rest and during coughing in the lidocaine group were significantly lower at 6, 12, and 24 hours postoperatively ( Conclusion: Compared with sufentanil-based PCIA, lidocaine-based PCIA significantly relieved postoperative pain and improved recovery quality after thoracoscopic lung surgery with fewer postoperative adverse events, which is a considerable choice for postoperative analgesia. Trial Registration: This study was retrospectively registered at the Chinese Clinical Trial Registry on March 1st, 2023 (number ChiCTR2300068840).

Indexed as

Analgesia, Patient-ControlledAnesthetics, LocalLidocainePostoperative PainSufentanilAdultAgedDouble-Blind MethodFemaleHumansMaleMiddle AgedAnesthetics, LocalLidocaineSufentanilintravenous lidocainepostoperative analgesiaquality of recoverythoracoscopic lung surgery

Identifiers

PMID40994902
PMCPMC12456753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.