Evidence map›Paper›PMID 40994879›Full record

ArticleNPJ cardiovascular health2025

Fine-tuning LLMs in behavioral psychology for scalable health coaching.

Sriya Mantena, Anders Johnson, Marily Oppezzo, Narayan Schütz, Alexander Tolas, Ritu Doijad, C Mikael Mattson, Allan Lawrie, Mariana Ramirez-Posada, Paul Schmiedmayer and 5 more

Abstract read
In one paragraph

Article in NPJ cardiovascular health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. State of clinical AI in 2026.BMJ digital health & AI · 2026
    Review
  4. AI and Digital Health: Personalizing Physical Activity to Improve Population Health.Circulation. Cardiovascular quality and outcomes · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sriya MantenaDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Anders JohnsonDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Marily OppezzoDepartment of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA USA.
Narayan SchützDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Alexander TolasDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Ritu DoijadDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
C Mikael MattsonDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Allan LawrieNational Heart and Lung Institute, Imperial College London, London, UK.
Mariana Ramirez-PosadaDepartment of Dermatology, Stanford University School of Medicine, Stanford, CA USA.
Paul SchmiedmayerDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Eleni LinosDepartment of Dermatology, Stanford University School of Medicine, Stanford, CA USA.
Abby C KingDepartment of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA USA.
Fatima RodriguezDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
Daniel Seung Kim *Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.ORCID 0000-0003-2971-1909
Euan A Ashley *Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.ORCID 0000-0001-9418-9577

Funding

CTSA K12 Program at StanfordK12TR004930 · NCATS · STANFORD UNIVERSITY · PI STEVEN M. ASCH, Eleni Linos · 2024 to 2026
$4.2M
Auracle: An AI-Enabled Telecare System to Support the Independence and Safety of Individuals with AD/ADRD and Other DementiasR44AG071211 · NIA · GEN-9, INC. · PI FAUCI, MARK A · 2021 to 2023
$2.9M
Opportunistic Atherosclerotic Cardiovascular Disease Risk Estimation at Abdominal CTs with Robust and Unbiased Deep LearningR01HL167974 · NHLBI · STANFORD UNIVERSITY · PI Imon Banerjee, Akshay Chaudhari · 2023 to 2026
$2.4M
Novel Incidental Calcium Evaluation (NICE)R01HL169345 · NHLBI · STANFORD UNIVERSITY · PI Imon Banerjee, Akshay Chaudhari · 2024 to 2026
$2.1M
Adherence Determinants in the Health Electronic Record Evaluation of Statins (ADHERES)R01HL168188 · NHLBI · STANFORD UNIVERSITY · PI Fatima Rodriguez · 2024 to 2026
$2.1M
Patient Oriented Research in Vulnerable Populations with Skin DiseaseK24AR075060 · NIAMS · STANFORD UNIVERSITY · PI Eleni Linos · 2019 to 2026
$1.6M
Novel digital tools for home-based monitoring of skin diseaseR01AR082109 · NIAMS · STANFORD UNIVERSITY · PI Eleni Linos · 2023 to 2026
$629k
NCATS NIH HHS K12 TR004930NHLBI NIH HHS L30 HL170306NHLBI NIH HHS R01 HL167974NHLBI NIH HHS R01 HL168188NHLBI NIH HHS R01 HL169345NIAMS NIH HHS K24 AR075060NIAMS NIH HHS R01 AR082109NIA NIH HHS R44 AG071211
6 · The paper itself

Abstract

Personalized, smartphone-based coaching improves physical activity but relies on static, human-crafted messages. We introduce My Heart Counts (MHC)-Coach, a large language model fine-tuned on the Transtheoretical Model of Change. MHC-Coach generates messages tailored to an individual's psychology (their "stage of change"), providing personalized support to foster long-term physical activity behavior change. To evaluate MHC-Coach's efficacy, 632 participants compared human-expert and MHC-Coach interventions encouraging physical activity. Among messages matched to an individual's stage of change, 68.0% (

Indexed as

Cardiovascular diseasesMetabolic diseases

Identifiers

PMID40994879
PMCPMC12454129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.