Evidence map›Paper›PMID 40994782›Full record

ArticleFrontiers in oral health2025

Research on the prevention of tooth demineralization and the effects and mechanisms of different mineralization solutions on the metabolism of

Renze Shen, Yongmei Tan, Jinchuan Zheng, Gang Xu, Mingli Lin, Zhanchao Ye, Lingna Han

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Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Renze Shen *Department of Stomatology, Zhongshan Hospital of Xiamen University, School of Stomatology, Xiamen University, Xiamen, China.
Yongmei Tan *Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Jinchuan Zheng *Department of Stomatology, People's Hospital Affiliated of Quanzhou Medical College, Quanzhou, China.
Gang Xu *Department of Medical Administration, Xiamen Emergency Medical Center, Xiamen, China.
Mingli Lin *Department of Stomatology, Zhongshan Hospital of Xiamen University, School of Stomatology, Xiamen University, Xiamen, China.
Zhanchao YeDepartment of Stomatology, Zhongshan Hospital of Xiamen University, School of Stomatology, Xiamen University, Xiamen, China.
Lingna HanDepartment of Stomatology, Zhongshan Hospital of Xiamen University, School of Stomatology, Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the preventive effects of various mineralization solutions on tooth demineralization and their influence on the metabolism of Methods: Pure water, Ca/P mineralization solution, Ca/P mineralization solution with fluoride, Ca/P mineralization solution with zinc, Ca/P mineralization solution with magnesium, and Ca/P mineralization solution with strontium (Sr) were prepared. Tooth fragments were immersed in these solutions at 37°C for 24 h. Surface morphology was examined by scanning electron microscopy (SEM). The relative proportions of surface elements were analyzed, and new substances formed on the tooth surface were identified. Acid-etching was performed to evaluate changes in anti-demineralization ability and wear resistance. Results: New substances were observed adhering to tooth surfaces by SEM; surfaces treated with zinc and Sr solutions were the roughest. Elemental proportion analysis indicated zinc had the highest adhesion potential, while Sr had the lowest. Newly formed substances included fluorapatite, magnesium hydroxide, and phosphate complexes. All experimental groups demonstrated improved acid resistance and good wear resistance. Sr treatment rendered tooth surfaces more hydrophilic and increased bacterial adhesion. All experimental groups inhibited acid production by

Indexed as

acid resistancedental cariesglycolysismetabolomeprevention

Identifiers

PMID40994782
PMCPMC12454444

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