Evidence map›Paper›PMID 40994761›Full record

ArticleCureus2025

Removal of Prostate Calcifications Prior to TULSA-PRO With the Aid of Real-Time Ultrasound Imaging: Our Technique and Experience.

Kyle Johnson, Rahul Mehan

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kyle JohnsonSurgery, Midwestern University Arizona College of Osteopathic Medicine, Glendale, USA.
Rahul MehanUrology, Dignity Health Mercy Gilbert Medical Center, Gilbert, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate calcifications can impede ultrasound energy propagation during transurethral ultrasound ablation (TULSA-PRO, Profound Medical Inc., Mississauga, ON, Canada). We instituted a pre-procedure screening protocol using low-dose pelvic computed tomography (CT) with ≤2-mm slices to detect calcifications larger than 3 mm along the planned ablation path; when obstructing deposits are present, we clear them immediately before treatment. Drawing on image-guided principles used in Aquablation (AquaBeam Robotic System, PROCEPT BioRobotics, San Jose, CA, USA), we correlate preoperative sagittal CT with real-time, stepper-mounted transrectal ultrasound (TRUS) to localize targeted prostate tissue for limited bipolar resection, while continuously visualizing the loop position on TRUS. In eight consecutive candidates with obstructive calcifications ≥3 mm, post-procedure low-dose CT confirmed clearance in every case, enabling uninterrupted continuation to the TULSA-PRO workflow. This streamlined, CT-referenced, TRUS-guided technique offers a practical pathway to preserve beam-path integrity without broad tissue debulking. The dataset of eight consecutive candidates with obstructive calcifications ≥3 mm reported here is original and has not been previously published in whole or in part.

Indexed as

computed tomographyfocal therapylocalized prostate cancerlow-dose ctprostate calcificationsprostatic calculitransrectal ultrasoundtransurethral ultrasound ablationtulsa-proultrasound-guided resection

Identifiers

PMID40994761
PMCPMC12455520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.