Evidence map›Paper›PMID 40994701›Full record

ArticleJournal of psychopathology and behavioral assessment2025

Anhedonia Relates to Increased Psychomotor Retardation Using an Instrumental Handwriting-Based Measure.

Riley E Maher, David M Klemballa, Sebastian Walther, Vijay A Mittal, Stewart A Shankman, Allison M Letkiewicz

Abstract read
In one paragraph

Article in Journal of psychopathology and behavioral assessment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riley E MaherDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL USA.
David M KlemballaDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL USA.
Sebastian WaltherTranslational Research Center, University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Vijay A MittalDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL USA.
Stewart A ShankmanDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL USA.
Allison M LetkiewiczDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL USA.ORCID 0000-0002-6812-8735

Funding

An examination of psychomotor disturbance in current and remitted MDD: An RDoC StudyR01MH118741 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MITTAL, VIJAY A, SHANKMAN, STEWART AARON · 2019 to 2023
$3.4M
Clarifying the Role of Psychomotor Retardation in Reward-Based Reinforcement Learning Deficits in MDD: A Computational and fMRI StudyK23MH129607 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Allison Letkiewicz · 2023 to 2026
$726k
NIMH NIH HHS K23 MH129607NIMH NIH HHS R01 MH118741
6 · The paper itself

Abstract

Psychomotor retardation (PmR) is a clinically important but understudied feature of depression. Available studies of PmR in depression have also been limited by the reliance on self-report and observation. Instrumental measures, which have been used to assess motor symptoms in neurological disorders, exhibit greater precision and sensitivity than self-report measures and can provide vital information in the clinical presentation. Hence, the present study sought to examine (a) whether depression (diagnosis and/or symptoms) is abnormally associated with an instrumental-based indictaor of PmR, velocity scaling (VS), a behavioral metric that reflects the ability to increase rate of movement across longer versus shorter distances, and (b) the reliability (internal consistency) of VS. A large sample of healthy controls ( Supplementary Information: The online version contains supplementary material available at 10.1007/s10862-025-10249-1.

Indexed as

AnhedoniaDepressionHandwritingInstrumental measureKinematicsPsychomotor retardationPsychomotor slowingReliabilityVelocity scaling

Identifiers

PMID40994701
PMCPMC12454474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.