Evidence map›Paper›PMID 40994667›Full record

ArticleStructural heart : the journal of the Heart Team2025

Outcomes of Intracardiac Echocardiography as the Primary Imaging Modality for Transcatheter Tricuspid Valve Procedures.

Anas I Zaqut, Ashtyn Chamberland, Scott M Chadderdon, Firas E Zahr

Abstract read
In one paragraph

Article in Structural heart : the journal of the Heart Team, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Intracardiac Echocardiography during Invasive Electrophysiological Procedures: a Scientific Statement of the European Heart Rhythm Association of the ESC, and the European Association of Percutaneous Cardiovascular Interventions of the ESC.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Guideline
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anas I ZaqutDivision of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon, USA.
Ashtyn ChamberlandDivision of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon, USA.
Scott M ChadderdonDivision of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon, USA.
Firas E ZahrDivision of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon, USA.

Funding

Training in Translational Science and Cardiovascular ResearchT32HL166128 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Nabil J Alkayed · 2023 to 2026
$2.0M
NHLBI NIH HHS T32 HL166128
6 · The paper itself

Abstract

Background: Tricuspid regurgitation (TR) is a high-mortality condition. While tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve replacement (TTVR) improve quality of life, their reliance on transesophageal echocardiography (TEE) poses challenges. Intracardiac echocardiography (ICE) offers a promising adjunct; however, data on safety and efficacy remain limited. This study evaluates procedural characteristics, safety, and outcomes as operators gain experience with ICE for tricuspid procedures. Methods: Twenty-two patients with symptomatic ≥ severe TR treated with TTVR or T-TEER at Oregon Health & Science University were enrolled. All procedures utilized ICE and TEE. Patients were divided into 2 cohorts: cohort 1 primarily used TEE with adjunctive ICE (10 cases: 4 TTVRs and 6 T-TEERs), while cohort 2 primarily used ICE with adjunctive TEE (12 cases: 5 TTVRs and 7 T-TEERs). Procedural characteristics and outcomes were compared. Results: Mean TTVR procedure time decreased from 124 ± 38 minutes in cohort 1 to 98 ± 36 minutes in cohort 2, while T-TEER times dropped from 115 ± 35 minutes to 108 ± 30 minutes. Fluoroscopy time decreased from 27 ± 10 minutes to 19 ± 9 minutes for TTVRs and from 27 ± 11 minutes to 25 ± 10 minutes for T-TEERs. The TR grade was reduced by ≥ 2 grades in all but 1 patient with no mortality, bleeding events, or hospitalizations across all cohorts. Conclusions: Primary ICE strategy improves procedural efficiency while maintaining comparable safety and efficacy. Larger studies are needed to confirm these findings, as only 22 patients participated in this study, limiting statistical robustness.

Indexed as

3D ICE3D TEEMultiplanar reconstructionT-TEERTTVR

Identifiers

PMID40994667
PMCPMC12455076

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.