Evidence map›Paper›PMID 40994619›Full record

ArticleClinical and translational radiation oncology2026

Comparative analysis of target volume coverage and liver exposure in high-dose-rate interstitial brachytherapy and

Sina Mansoorian, Svenja Hering, Jan Hofmaier, Yuqing Xiong, Helmut Weingandt, Maya Rottler, Franziska Walter, Paul Rogowski, Max Seidensticker, Jens Ricke and 3 more

Abstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sina MansoorianDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Svenja HeringDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Jan HofmaierDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Yuqing XiongDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Helmut WeingandtDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Maya RottlerDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Franziska WalterDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Paul RogowskiDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Max SeidenstickerDepartment of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.
Jens RickeDepartment of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.
Claus BelkaDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Chukwuka EzeDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study compared the plan quality and dosimetric parameters of single-fraction (SF) MR-LINAC (MRL)-based stereotactic body radiotherapy (SBRT) with delivered high-dose-rate interstitial brachytherapy (HDR-iBT) for colorectal liver metastases (CRLM). Methods: Between August 2017 and March 2019, 26 patients with a total of 45 CRLM were treated in 28 sessions using HDR-iBT with 1 × 25 Gy and were retrospectively included in this study. For each patient, an Results: Median GTV was 3.83 cc (range: 0.13-92.58 cc) and median PTV Conclusion: Our comparison indicates MRL-based SBRT to liver lesions is feasible, achieving adequate target volume coverage without clinically relevant violations of organ-at-risk (OAR) constraints.

Indexed as

Colorectal liver metastasisCT-guided interstitial brachytherapyDosimetryHDR interstitial brachytherapyIn silico analysisSABRSBRTStereotactic ablative radiotherapy

Identifiers

PMID40994619
PMCPMC12454280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.