Evidence map›Paper›PMID 40994554›Full record

ArticleJournal of magnetic resonance open2025

Magnetic resonance coil prototyping and implementation for multi-nuclear small animal imaging.

Alexander I Zavriyev, Benjamin J Yoon, John Choi, Bukola Y Adebesin, Paul S Jacobs, Gabor Mizsei, Molly M Sheehan, Stephen Kadlecek, Terence P F Gade

Abstract read
In one paragraph

Article in Journal of magnetic resonance open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander I ZavriyevThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.ORCID 0000-0003-3383-0724
Benjamin J YoonThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.
John ChoiDepartment of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, United States of America.
Bukola Y AdebesinThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.
Paul S JacobsDepartment of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, United States of America.
Gabor MizseiThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.
Molly M SheehanThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.
Stephen KadlecekThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.
Terence P F GadeThe Metabolic Discovery Center at Penn, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States of America.

Funding

Noninvasive assessment of IDH mutation status in intrahepatic cholangiocarcinomaF31CA291090 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Alexander Zavriyev · 2024 to 2026
$149k
NCI NIH HHS F31 CA291090
6 · The paper itself

Abstract

Purpose: Heteronuclear MR imaging allows investigation into unique disease states. These approaches often require radiofrequency coil designs that are customized for the imaging probe and target. This study addresses the challenges of rapidly prototyping heteronuclear MR coils for small animal imaging applications. We propose the use of 3D-printing molds for inductor shaping connected to a printed circuit board (PCB) via a flexible coaxial cabling to enhance coil reproducibility and utility. Methods: A rapid prototyping pipeline was developed for constructing affordable and sensitive coils. The reproducibility of 3D-printed mold inductors was compared to hand-turned and PCB inductors. A theoretical treatment of the effect of PCB/inductor coupling on tuning/matching conditions was verified under a variety of practical conditions, yielding a simplified approach which allows component selection and assembly with minimal empirical development. Results: The 3D-printed mold inductors demonstrated higher reproducibility than hand-turned inductors, and PCB RF coils demonstrated the highest reproducibility. The average resonance return loss (S Conclusion: The developed prototyping pipeline represents a rapid and effective approach for designing highly reproducible coils with a desired resonance frequency and size that can easily be adapted for a variety of experimental set-ups. All design resources - including an interactive coil-parameter calculator, 3D-models of inductor molds, and PCB files - are available for use at https://medcap.ai/mr-coil-calculator.

Indexed as

Coil designDeuteriumHetero-nuclearHyperpolarizationMR CoilsSmall animal imaging

Identifiers

PMID40994554
PMCPMC12456740

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.