The current role of surgery for single brain metastases.

Tunc Faik Ersoy, Daniel Brainman, Diyan Dimov, Roland Coras, Björn Berger, Florian Weissinger, Matthias Simon

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In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tunc Faik ErsoyDepartment of Neurosurgery, University Hospital OWL, Evangelisches Klinikum Bethel, Bielefeld, Germany.

Daniel BrainmanDepartment of Neurosurgery, University Hospital OWL, Evangelisches Klinikum Bethel, Bielefeld, Germany.

Diyan DimovDepartment of Neurosurgery, University Hospital OWL, Evangelisches Klinikum Bethel, Bielefeld, Germany.

Roland CorasDepartment of Neuropathology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

Björn BergerDepartment of Neuroradiology, University Hospital OWL, Evangelisches Klinikum Bethel, Bielefeld, Germany.

Florian WeissingerDepartment of Hematology, Oncology and Palliative Care, University Hospital OWL, Evangelisches Klinikum Bethel, Bielefeld, Germany.

Matthias SimonDepartment of Neurosurgery, University Hospital OWL, Evangelisches Klinikum Bethel, Bielefeld, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Surgery for singular brain metastases (BM) aims to improve survival by providing control of CNS disease. This concept may need to be refined against the background of recent advances in medical and radiation oncology. In particular there is a debate about the prognostic role of residual tumor. Research question: Does extent of resection influence overall- and cerebral progression-free-survival as well as functional outcome? Materials and methods: This retrospective series comprised 202 patients with single BM who underwent surgery 2015-2023. All patients underwent pre- and postoperative MR imaging. Results: Surgical indications included a tumor too large for radiosurgery (≥15.0 cm Conclusion: Small tumor remnants may have limited impact on survival. In the era of targeted therapies tissue acquisition for molecular analysis is an increasingly important indication for BM surgery.

Indexed as

Functional outcomeMRIProgression-free survivalResidual tumorSingle brain metastasisSurvival

Identifiers

PMID40994525

DOI10.1016/j.bas.2025.105600

PMCPMC12455075

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