Evidence map›Paper›PMID 40993795›Full record

ReviewParasites & vectors2025

Microbiome diversity in mosquitoes and sand flies: implications for vector competence.

Gnanasekar Ragini, Mahima K Mani, Rohit Sharma, Nikhil Bharadwaj, Muthukumaravel Subramanian, Shriram Ananganallur Nagarajan, Manju Rahi

Abstract readReview
In one paragraph

Review in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gnanasekar RaginiDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India.
Mahima K ManiDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India.
Rohit SharmaDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India. rohitah.sharma@gmail.com.
Nikhil BharadwajDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India.
Muthukumaravel SubramanianDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India.
Shriram Ananganallur NagarajanDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India. shriram.an@icmr.gov.in.
Manju RahiDivision of Vector Biology and Control, ICMR-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, 605006, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquitoes and sand flies are the most important vectors of several human diseases. A comprehensive analysis of the diversity and composition of the microbiome in mosquitoes and sandflies is important. It emphasises shared traits and distinctive differences between these vector species. Recent findings have demonstrated that physiological, environmental and ecological factors influence the diversity of these microbial communities. A deeper understanding of the functional roles of specific microbial taxa, such as their ability to modulate host immune responses or directly interact with pathogens, reveals exciting opportunities for innovative vector management strategies. These strategies could leverage microbiome manipulation to disrupt the transmission of disease-causing agents. However, despite notable advancements, critical gaps remain in unravelling the precise mechanisms by which these microbiome compositions influence vector competence. Ultimately, this understanding can be leveraged to harness the potential of microbiome-based interventions in reducing the burden of vector-borne diseases. This review explores the intricate relationships between microbial communities and key vectors, highlighting how these interactions influence the dynamics of pathogen transmission.

Indexed as

CulicidaeInsect VectorsMicrobiotaMosquito VectorsPsychodidaeAnimalsBiodiversityHumansVector Borne DiseasesDiversityGut microbiomeMicrobiomeMosquitoSandfliesVector competence

Identifiers

PMID40993795
PMCPMC12462317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.