Evidence map›Paper›PMID 40993694›Full record

ArticleTrials2025

Protocol update to a study protocol for the Multimodal Approach to Preventing Suicide in Schools (MAPSS) project: a regionally based randomised trial of an integrated response to suicide risk among secondary school students.

Samuel McKay, Michelle Lamblin, India Bellairs-Walsh, Maria Veresova, Bridget Kenny, Eleanor Bailey, Sadhbh J Byrne, Jane Pirkis, Cathrine Mihalopoulos, Matthew J Spittal and 7 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Samuel McKay, Orygen, Parkville, Australia. samuel.mckay@orygen.org.au.ORCID http://orcid.org/0000-0003-2700-5285
Michelle Lamblin, Orygen, Parkville, Australia.
India Bellairs-Walsh, Orygen, Parkville, Australia.
Maria VeresovaViolet Vines Marshman Research Centre, La Trobe Rural Health School, La Trobe University, Bendigo, Australia.
Bridget Kenny, Orygen, Parkville, Australia.
Eleanor Bailey, Orygen, Parkville, Australia.
Sadhbh J ByrneDepartment of Psychology, Maynooth University, Maynooth, Co. Kildare, Ireland.
Jane PirkisCentre for Mental Health and Community Wellbeing, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Cathrine MihalopoulosMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Matthew J SpittalCentre for Mental Health and Community Wellbeing, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Simon Rice, Orygen, Parkville, Australia.
Ellie Brown, Orygen, Parkville, Australia.
Sarah HetrickPsychological Medicine, Faculty of Medical and Health Sciences, Te Ata Hāpara Suicide Prevention Research Centre, Te Aro Hāro Centre for Infant Child and Adolescent Mental Health, The University of Auckland, Auckland, New Zealand.
Matthew Hamilton, Orygen, Parkville, Australia.
Hok Pan Yuen, Orygen, Parkville, Australia.
Yong Yi LeeMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Jo Robinson, Orygen, Parkville, Australia.

Funding

National Health and Medical Research Council GNT1153051National Health and Medical Research Council Investigator Grant GNT2025205National Health and Medical Research Council Investigator Grant GNT2026408National Health and Medical Research Council Investigator Grant ID2008460University of Melbourne Dame Kate Campbell
6 · The paper itself

Abstract

backgroundThis update outlines amendments to the MAPSS trial protocol in response to both the COVID-19 pandemic and broader feasibility considerations. While many changes were necessary to navigate pandemic-related disruptions-such as school closures and remote learning-others were made to improve feasibility in the school-based setting, independent of COVID-19. The protocol was updated to align with public health guidelines and general school practices, ensuring feasibility for continued school participation and increased support and flexibility for school communities.

methodsKey adjustments included changes to participant-facing documentation, including implementing digital consent processes, extending timelines for participant recruitment and participation, and enhancing remote engagement strategies. Modifying outcome measures and risk management protocols, including adverse event reporting, ensured both participant safety and data continuity. Lastly, new study measures were added, such as a custom-designed questionnaire to assess study acceptability. Despite the updates, the core trial design, eligibility criteria, and primary outcomes remained unchanged.

conclusionThese protocol amendments reflect the pragmatic challenges of conducting school-based mental health research during a global pandemic and as part of ongoing efforts to enhance feasibility. The adjustments enabled the trial to proceed safely, prioritizing participant engagement and maintaining alignment with public health measures. TRIAL REGISTRATIONS: Australian New Zealand Clinical Trial Registry, ACTRN12621000279820, originally registered on 12 March 2021, and currently awaiting update approval. Australian New Zealand Clinical Trial Registry, ACTRN12621000770864, originally registered on 21st June 2021, and updated on 16th February 2025.

Indexed as

COVID-19School Health ServicesSchoolsStudentsSuicide PreventionAdolescentFeasibility StudiesFemaleHumansMaleRandomized Controlled Trials as TopicSARS-CoV-2SuicideICBTPsychoeducationSchoolsScreeningSuicide prevention

Identifiers

PMID40993694
PMCPMC12462089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.