Evidence map›Paper›PMID 40993680›Full record

ArticleBMC oral health2025

Evaluation of color stability and material surface stability of different types of clear aligners under curcumin staining in vitro.

Ketai He, Mingjie Xu, Wen Liao, Yang Yao

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ketai He *State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Mingjie Xu *State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Wen LiaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China. liaowenssw@126.com.
Yang YaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China. yaoyang9999@126.com.

Funding

International orthodontics foundation No. IOF2022Y08the Natural Science Foundation of Sichuan Province, China No.2024NSFSC0762
6 · The paper itself

Abstract

Aesthetics play a crucial role in patients' choice of orthodontic clear aligners, as poor color stability can compromise their appearance during wear. This study aimed to evaluate the color and surface stability of different types of orthodontic clear aligners exposed to various concentrations of curcumin solutions in vitro. Four types of clear aligners (Invisalign, Angelalign, Spark, and Dreve), along with non-thermoformed Dreve film, were cut into 5 mm × 5 mm squares and immersed in curcumin solutions of different concentrations and a control solution. The concentrations were determined based on the curcumin content in curry. Anhydrous ethanol was used as the solvent, which may influence surface properties and color stability and partially simulating damage caused by alcohol consumption or bacterial metabolites. After immersion for 12 h and 7 days, the squares were ultrasonically cleaned, and color changes were measured using a colorimeter, then converted to National Bureau of Standards (NBS) units. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) were used to observe surface characteristics before and after staining. After 12 h of immersion in 10 µg/ml solutions, all samples except the Dreve film exhibited at least an "Appreciable: marked change," with Angelalign showing a more pronounced color alteration. After 7 days of immersion, most materials displayed color changes ranging from "Much: extremely marked change" to "Very much: change to other colors." Across all concentrations and time points, Invisalign aligners exhibited significantly higher ΔE* values than Dreve (P < 0.05). Although SEM and AFM results were not entirely consistent, both indicated that PU-based aligners were more susceptible to surface morphology changes than PET-G-based aligners. Enhancing the aesthetic color stability of orthodontic materials could contribute to improved clinical outcomes.

Indexed as

CurcuminOrthodontic Appliance DesignColorColorimetryEthanolHumansMaterials TestingMicroscopy, Atomic ForceMicroscopy, Electron, ScanningSolventsSurface PropertiesTime FactorsCurcuminEthanolSolventsClear alignersColor stabilityMaterial surfacePolymersStaining

Identifiers

PMID40993680
PMCPMC12461948

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.