Evidence map›Paper›PMID 40993665›Full record

ArticleBMC public health2025

Using social influencers for public health education on antibiotic use and antimicrobial resistance: protocol for a quasi-experimental study.

Angela Chow, Seema Aithal, Huiling Guo, May O Lwin, Zoe Jane-Lara Hildon

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06998576 (Different Strokes for Different Folks - Leveraging on Social Networks for Public Health Education on Antibiotic Use and Antimicrobial Resistance), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06998576 narecruitingnot on this map

Different Strokes for Different Folks - Leveraging on Social Networks for Public Health Education on Antibiotic Use and Antimicrobial Resistance

TypeinterventionalSponsorTan Tock Seng HospitalRan2025 to 2027Enrolled3,300ConditionsCommunity MembersArmsAnimated educational video on antibiotic use
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angela ChowDepartment of Epidemiology and Preventive Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. angela_chow@ttsh.com.sg.
Seema AithalDepartment of Epidemiology and Preventive Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
Huiling GuoDepartment of Epidemiology and Preventive Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
May O LwinLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Zoe Jane-Lara HildonSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

Funding

National Medical Research Council MOH-CSAINV22jul-0010
6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) is driven by the inappropriate use of antibiotics. "One-size-fits-all" campaigns have demonstrated little impact in increasing public knowledge of antibiotic use and AMR. Whilst healthcare providers are the most trusted sources of health information, only half of the adult population have a healthcare encounter annually. Their limited reach suggests inadequacies in communication channels and a need for mobilization of community-based non-healthcare influencers to increase accessibility to information on antibiotic use and AMR. Whilst the engagement of community barbershops and hair salons as health advocates has been well studied and shown to be effective for health education, there is no study to date harnessing ubiquitous neighborhood food establishments for health education and none assessing the comparative effectiveness of various types of neighborhood establishments as health advocates. This study protocol describes research which aims to compare the effectiveness of health education facilitated by neighborhood food and beauty establishments, versus neighborhood clinics, in increasing the public's knowledge of antibiotic use and AMR, and improving antibiotic behaviors.

methodsA quasi-experimental study will be conducted in highly frequented healthcare clinics, and beauty and food establishments in two neighborhoods in Central Singapore. Clients (patients/patrons) aged ≥ 21 years visiting the chosen establishments will be invited to participate in the one-year-long study by scanning the QR code on recruitment posters placed within the establishment premises. Participants will receive educational information on antibiotic use and AMR via a two-minute animated video, developed based on the knowledge needs and media preferences of the community. Outcome measures, namely participants' knowledge of antibiotic use and AMR, and antibiotic use practices will be assessed via self-administered surveys conducted at five longitudinal time-points: pre-intervention, immediate post-intervention, 1-month post-intervention, 3-month post-intervention, and 6-month post-intervention. Additionally, the reach and implementation fidelity of the intervention at the participating study sites will be assessed. DISCUSSION: Findings from the study will enable a more comprehensive understanding of the potential reach and effects of health education facilitated by neighborhood retail establishments in relation to neighborhood healthcare clinics, enabling better insights into selecting health message outreach options.

trial registrationClinicalTrials.gov NCT06998576; https://clinicaltrials.gov/study/NCT06998576 ; first posted on 2025-05-31, last update posted on 2025-06-05.

Indexed as

Anti-Bacterial AgentsDrug Resistance, MicrobialHealth EducationPublic HealthAdultHealth Knowledge, Attitudes, PracticeHumansMaleNon-Randomized Controlled Trials as TopicResidence CharacteristicsSingaporeAnti-Bacterial AgentsAnimated educational videoAntibiotic useAntimicrobial resistanceCommunity health communicationHealthcare clinicsNeighborhood food and beauty establishmentsPublic health education

Identifiers

PMID40993665
PMCPMC12462344

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.