Evidence map›Paper›PMID 40993572›Full record

ArticleBMC pregnancy and childbirth2025

The relationship between parity, delivery mode, maternal age at delivery, and bone mineral density: a cross-sectional study.

Jinlong Ma, Xiang Li, Qiuyue Li, Zhenqian Sun, Hongliang Wang, Yunzhen Chen, Guangjun Jiao

Abstract read
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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jinlong Ma *Shandong University Cheeloo College of Medicine, No.107 Road, Lixia District, Jinan, Shandong, 250000, China.
Xiang Li *Shandong University Cheeloo College of Medicine, No.107 Road, Lixia District, Jinan, Shandong, 250000, China.
Qiuyue LiDepartment of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Zhenqian SunShandong University Cheeloo College of Medicine, No.107 Road, Lixia District, Jinan, Shandong, 250000, China.
Hongliang WangShandong University Cheeloo College of Medicine, No.107 Road, Lixia District, Jinan, Shandong, 250000, China.
Yunzhen Chen *Shandong University Cheeloo College of Medicine, No.107 Road, Lixia District, Jinan, Shandong, 250000, China. qilucyz@yeah.net.
Guangjun Jiao *Shandong University Cheeloo College of Medicine, No.107 Road, Lixia District, Jinan, Shandong, 250000, China. jiaoguangjun@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs a neuro-psycho-social event, delivery can significantly impact maternal health. However, the association between childbirth and maternal bone health remains unclear, warranting further investigation.

methodsOur study was based on data from the National Health and Nutrition Examination Survey (NHANES) (2005-2020). We employed propensity score matching, Welch's two-sample t-test, linear mixed models, and partial correlation analysis to assess the relationship between delivery-related factors (parity, delivery mode, maternal age at delivery) and bone mineral density (BMD) of the lumbar spine and femoral neck.

resultsWe obtained 5726 participants. Welch's two-sample t-test showed that delivered subjects had lower mean BMD of the lumbar spine and femoral neck. The data from the linear mixed model showed a decrease in BMD of femoral neck and a decrease in BMD of lower spine in subjects who have delivered compared to those who had not. The same analyses showed lower BMD. Partial correlation analysis showed a negative correlation between age at delivery and BMD in women who gave delivery vaginally.

conclusionsParity and advanced maternal age at delivery are associated with decreased BMD. Notably, vaginal delivery is linked to reduced femoral neck BMD, a novel finding highlighting the potential biomechanical impact of this delivery mode.

Indexed as

Bone DensityDelivery, ObstetricMaternal AgeParityAdultCross-Sectional StudiesFemaleFemur NeckHumansLumbar VertebraeMiddle AgedNutrition SurveysPregnancyYoung AdultBone mineral densityDeliveryParityWomen

Identifiers

PMID40993572
PMCPMC12462025

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.