SynthesisBMC public health2025
Determinants of neonatal mortality in sub-Saharan Africa: systematic review and meta-analysis of adverse newborn conditions.
Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The trial behind it
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Who cites it
6 citing papers in PubMed.
- Village-level surveillance of neonatal disease with integrated real-time dashboards and quality-control in Uganda.medRxiv : the preprint server for health sciences · 2026Article
- Early neonatal mortality and its associated factors at Doctor Bogalech Gebre Memorial General Hospital, Central Ethiopia: A cross-sectional study.Scientific reports · 2026Article
- Burden, clinical characteristics, and determinants of neonatal sepsis in a tertiary hospital in North-Central Nigeria: a retrospective study.BMC pediatrics · 2026Article
- The Six Delays Model: expanding the three delays model with evidence from Madagascar for maternal referrals in LMICs.BMJ global health · 2026Review
- Neonatal Mortality in Burkina Faso: An Exploratory Analysis of Determinants and Geospatial Inequalities.International journal of public health · 2025Article
- Incidence, Mortality, and Premature Mortality From Neonatal Disorders in Eastern Sub-Saharan Africa, From 1990 to 2023.Sage open pediatricsArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary studies conducted in sub-Saharan Africa (SSA) reported an inconsistent association between adverse newborn conditions and neonatal mortality. Thus, this review was aimed at assessing the association of adverse newborn conditions with neonatal mortality and generating a pooled estimate of the association using a large sample size from primary studies conducted in SSA.
methodsDatabases (PubMed, ScienceDirect, and Hinari for health via Research4Life) and gray literature sources were accessed. Relevant studies were retrieved from related studies via snowballing. To search the studies, a combination of medical subject headings (MeSH terms) using Boolean operators and key words related to neonatal mortality were considered. Full-text articles published from observational studies in SSA were included. Higgins's I
resultsA total of 36 studies were included to answer the review questions. The pooled odds ratios (OR) indicated that adverse newborn conditions: preterm birth [(OR = 3.76, 95% CI 2.92, 4.84), I
conclusionsNeonatal mortality in sub-Saharan Africa was significantly associated with adverse newborn conditions, highlighting the need to strengthen essential newborn care practices. Maternal health services such as good antenatal care services, nutrition during pregnancy, quality intrapartum care, and infection prevention are also fundamental to reducing the risk of neonatal mortality in SSA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.