ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026
Can bone SPECT/CT and 18 F-NaF PET/CT diagnose the cause of persistent pain due to motion sparing devices: a case series.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeCan positron emission tomography/CT (18 F-NaF PET/CT) and Bone single-photon emission CT (SPECT/CT) be used to diagnose the cause of persistent pain in motion-sparing devices? Interspinous devices (ISD) and cervical disc arthroplasty (CDA) are used increasingly. While a desired outcome is achieved in a portion of these patients, others develop persistent postoperative symptoms. Etiology of these symptoms is diagnosed with imaging such as x-ray, computed tomography (CT), or magnetic resonance imaging (MRI). Despite these modalities, there is a subset of patients with persistent pain who remain without a diagnosis. In these patients, Bone SPECT/CT and 18F-NaF PET/CT can aid in the detection of complications including implant loosening, screw loosening, and infection.
methodsRetrospective review was performed at a tertiary care center to identify patients with persistent pain following placement of motion sparing devices and underwent Bone SPECT/CT or 18 F-NaF PET/CT.
resultsSix patients who underwent 99mTc-MDP Bone SPECT/CT or 18 F-NaF PET/CT for persistent postoperative symptoms following ISD placement or CDA were included. Of the six patients, four patients demonstrated uptake on 99mTc-MDP Bone SPECT/CT or 18 F-NaF PET/CT. Based on imaging findings, one patient underwent removal of the artificial disc, two patients were offered but declined surgery for device removal, and one patient was offered a spinal cord stimulator trial with the option of device removal if pain persisted.
conclusion99mTc-MDP Bone SPECT/CT and 18 F-NaF PET/CT can guide surgical recommendations for patients with persistent symptoms following ISD placement or CDA.
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