Evidence map›Paper›PMID 40993159›Full record

ArticleScientific reports2025

A repeated awakening study exploring the capacity of complexity measures to capture dreaming during propofol sedation.

Imad J Bajwa, Andre S Nilsen, René Skukies, Arnfinn Aamodt, Gernot Ernst, Johan F Storm, Bjørn E Juel

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cognitive Processing and EEG Complexity.Entropy (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Brain responses vary in duration-modeling strategies and challenges.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Imad J BajwaBrain Signaling Group, Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317, Oslo, Norway. imadjb@uio.no.
Andre S NilsenBrain Signaling Group, Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317, Oslo, Norway.
René SkukiesBrain Signaling Group, Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317, Oslo, Norway.
Arnfinn AamodtBrain Signaling Group, Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317, Oslo, Norway.
Gernot ErnstVestre Viken Klinisk Nevrovitenskap, Kongsberg Hospital, 3612, Kongsberg, Norway.
Johan F StormBrain Signaling Group, Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317, Oslo, Norway.
Bjørn E JuelBrain Signaling Group, Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317, Oslo, Norway.

Funding

Human Brain Project 945539Norges Forskningsråd 262950/F20)
6 · The paper itself

Abstract

Patients undergoing general anesthesia are often assumed to be unconscious. However, it is known that conscious experiences in the form of dreams occur even in unresponsive states induced by anesthetics. Here, we recorded resting state electroencephalography (EEG) as well as EEG combined with TMS perturbations in 20 healthy participants during propofol sedation. Participants were repeatedly awoken from deep sedation and asked immediately whether they had experiences just before waking up and what they experienced. Out of the 52 attempted awakenings in this study, 24 produced reports of having had an experience, while there were 5 reports of no experience. In the remaining 23 attempts, the subject was either unarousable or the report too incoherent to provide information about their experience prior to awakening. We then tested whether two different consciousness measures based on EEG complexity-the state transitions perturbational complexity index (PCI

Indexed as

Deep SedationDreamsHypnotics and SedativesPropofolWakefulnessAdultConsciousnessElectroencephalographyFemaleHumansMaleYoung AdultHypnotics and SedativesPropofol

Identifiers

PMID40993159
PMCPMC12460656

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.