Evidence map›Paper›PMID 40993111›Full record

ArticleNature communications2025

CD103

Eleonora Terrabuio, Enrica Caterina Pietronigro, Alessandro Bani, Vittorina Della Bianca, Carlo Laudanna, Barbara Rossi, Giulia Finotti, Bruno Santos-Lima, Elena Zenaro, Ermanna Turano and 12 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Aged circulating CD8Immunity · 2026
    Article
  6. Article
  7. Article
  8. Immune signaling and function in neurodegeneration.The Journal of clinical investigation · 2026
    Review
  9. Immune dysfunction in Alzheimer disease.Nature reviews. Neuroscience · 2026
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Eleonora TerrabuioDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy. eleonora.terrabuio@univr.it.ORCID http://orcid.org/0000-0002-1999-6333
Enrica Caterina PietronigroDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.ORCID http://orcid.org/0000-0001-7661-2247
Alessandro BaniDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.
Vittorina Della BiancaDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.
Carlo LaudannaDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.ORCID http://orcid.org/0000-0003-4050-1056
Barbara RossiDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.ORCID http://orcid.org/0000-0003-4711-1528
Giulia FinottiCentro Piattaforme Tecnologiche (CPT), University of Verona, Verona, Italy.
Bruno Santos-LimaDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.
Elena ZenaroDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.ORCID http://orcid.org/0000-0003-3928-6272
Ermanna TuranoDepartment of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Gabriele TosadoriDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.
Matteo CalgaroDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, Verona, Italy.ORCID http://orcid.org/0000-0002-3056-518X
Nicola VituloDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, Verona, Italy.ORCID http://orcid.org/0000-0002-9571-0747
Monica CastellucciCentro Piattaforme Tecnologiche (CPT), University of Verona, Verona, Italy.
Daniela CecconiThe Center for Biomedical Computing (CBMC), University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-7314-8941
Jessica BrandiDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, Verona, Italy.ORCID http://orcid.org/0000-0003-1643-7023
Nikolaos VareltzakisDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.ORCID http://orcid.org/0009-0007-8386-9172
Fabiana MainieriDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.
Antonella CaloreDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.ORCID http://orcid.org/0009-0000-2107-594X
Gabriele AngeliniDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy.
Bruno BonettiNeurology Unit A, Azienda Ospedaliera Universitaria Integrata of Verona, P. le Stefani, Verona, Italy.
Gabriela ConstantinDepartment of Medicine, University of Verona, Strada le Grazie 8, Verona, Italy. gabriela.constantin@univr.it.ORCID http://orcid.org/0000-0001-8978-3539

Funding

EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013)) 693606 IMPEDEEC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101069397 NeutrADEC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 695714 Immunoalzheimer
6 · The paper itself

Abstract

Immune mechanisms contribute to the neuropathology of Alzheimer's disease (AD) but the role of adaptive immune cells is unclear. Here we show that the brain CD8

Indexed as

Alzheimer DiseaseAntigens, CDCD8-Positive T-LymphocytesGranzymesIntegrin alpha ChainsAgedAnimalsBrainCognitive DysfunctionDisease Models, AnimalFemaleHumansInflammationLymphocyte Function-Associated Antigen-1MaleMicealpha E integrinsAntigens, CDGranzymesIntegrin alpha ChainsLymphocyte Function-Associated Antigen-1tau Proteins

Identifiers

PMID40993111
PMCPMC12460627

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.