Evidence map›Paper›PMID 40993042›Full record

ReviewExperimental physiology2026

Human adaptation to high-altitude: A contemporary comparison of the oxygen cascade in Andean, Tibetan and Ethiopian highlanders.

Ayechew A Getu, Melissa Ilardo, Joshua C Tremblay, Jay M J R Carr, Vitalie Faoro, Philip N Ainslie

Abstract readReviewComparative Study
In one paragraph

Review in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayechew A GetuCentre for Heart, Lung and Vascular Health, University of British Columbia, Okanagan, British Columbia, Canada.ORCID https://orcid.org/0000-0002-1192-3359
Melissa IlardoDepartment of Biomedical Informatics, University of Utah School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Joshua C TremblayCardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.ORCID https://orcid.org/0000-0002-1667-294X
Jay M J R CarrInstitute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.
Vitalie FaoroResearch Unit in Cardio-respiratory Physiology, Exercise & Nutrition, Faculty of Human Motor Sciences, Université libre de Bruxelles, Brussels, Belgium.
Philip N AinslieCentre for Heart, Lung and Vascular Health, University of British Columbia, Okanagan, British Columbia, Canada.

Funding

Canada Research Chairs (Chaires de recherche du Canada)Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC)
6 · The paper itself

Abstract

Human populations native to high altitude have evolved distinct physiological adaptations to chronic hypoxia. This adaptation is evident in the O

Indexed as

AcclimatizationAdaptation, PhysiologicalAltitudeOxygenOxygen ConsumptionCardiac OutputEthiopiaHumansHypoxiaTibetOxygenacclimatizationadaptationhigh altitudenative highlandersoxygen cascade

Identifiers

PMID40993042
PMCPMC12949176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.