Evidence map›Paper›PMID 40993003›Full record

Trial reportBritish journal of anaesthesia2025

Efficacy of a lung recruitment manoeuvre in children undergoing general anaesthesia with a supraglottic airway.

Ricarda Lippuner, Charlotte Pellaud, Markus Huber, Robert Greif, Nicola Disma, Thomas Riva, Alexander Fuchs, Thomas Riedel

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05672329 (Functional Residual Capacity Under Apnoeic Oxygenation with Different Flow Rates in Children), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05672329 nacompletednot on this map

Functional Residual Capacity Under Apnoeic Oxygenation with Different Flow Rates in Children: a Single-centre Prospective Randomized Controlled Trial

TypeinterventionalSponsorThomas RivaRan2023 to 2024Enrolled108ConditionsApnea, Anesthesia, Intubation Complication, Children, OnlyArms0.2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 4 L/kg/min, FiO2 1.0 + continuous jaw thrust, 2 L/kg/min using OptiFlow-Switch system, FiO2 1.0 + continuous jaw thrust
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ricarda LippunerDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Charlotte PellaudDivision of Paediatric Intensive Care Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Markus HuberDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Robert GreifMedical Faculty, University of Bern, Bern, Switzerland.
Nicola DismaUnit for Research in Anaesthesia, IRCCS Istituto Giannina Gaslini, Genova, Italy. Electronic address: nicoladisma@gaslini.org.
Thomas RivaDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Alexander FuchsDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Thomas RiedelDivision of Paediatric Intensive Care Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung atelectasis is a well-recognised consequence of general anaesthesia in children and can cause poor oxygenation. Lung recruitment manoeuvre has been proposed as a strategy to counteract atelectasis. In this feasibility study, we evaluated whether a recruitment manoeuvre in children with a supraglottic airway restores end-expiratory lung volume (EELV) to baseline using electrical impedance tomography.

methodsAfter ethics committee approval (BASEC 2022-01833), we included children (ASA physical status 1-2, 10-20 kg) scheduled for anaesthesia with a supraglottic airway. We performed a recruitment manoeuvre by setting an anaesthesia machine to spontaneous breathing with a 3 L min

resultsOf the 95 eligible children, we analysed 74 datasets. The median (95% confidence interval) estimated difference in EELV after recruitment manoeuvre vs baseline was -0.9 ml kg

conclusionsIn children undergoing general anaesthesia with the use of a supraglottic airway, a recruitment manoeuvre effectively restores EELV to baseline. CLINICAL

trial registrationNCT05672329.

Indexed as

Airway ManagementAnesthesia, GeneralIntubation, IntratrachealLaryngeal MasksPulmonary AtelectasisChildChild, PreschoolElectric ImpedanceFeasibility StudiesFemaleHumansInfantLungMaleairway pressureanaesthesiaatelectasislung volumepaediatricsrecruitment manoeuvresrespiratory physiology

Identifiers

PMID40993003
PMCPMC12597366

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.