SynthesisBJOG : an international journal of obstetrics and gynaecology2026
Cardiovascular and Renal Outcomes Following Acute Kidney Injury in Pregnancy: A Systematic Review and Meta-Analysis.
Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
backgroundAcute kidney injury (AKI) in pregnancy is associated with adverse maternal and foetal outcomes. However, there is limited evidence regarding cardiac and renal outcomes associated with AKI in pregnancy.
objectiveTo quantify and perform a meta-analysis of the risk of adverse cardiovascular and renal outcomes following AKI in pregnancy. SEARCH STRATEGY: A systematic search of MEDLINE, Cochrane Library and EMBASE from inception until 23 January 2024. SELECTION CRITERIA: Studies investigating adverse cardiovascular and renal outcomes in pregnant patients with AKI. DATA COLLECTION AND ANALYSIS: Two reviewers independently performed screening, data extraction and quality assessment. A random-effects model was used to estimate risk. MAIN
resultsA total of 17 studies were included with 50 285 836 pregnant women, of which 36 806 women were affected by AKI. Our evidence synthesis showed that AKI in pregnancy is associated with a 52-fold increase in the risk of composite adverse renal outcomes (OR 52.37; 95% CI 4.67-587.63), a 23-fold increase in the risk of heart failure (OR 22.55; 95% CI 4.39-115.71) and stroke (OR 22.92; 95% CI 2.32-226.65), as well as a 9.3-fold and 3.9-fold increased risk of maternal mortality (OR 9.26; 95% CI 2.53-33.96) and intensive care unit admission (OR 3.86; 95% CI 1.93-7.71), respectively.
conclusionsThe study shows that AKI in pregnancy is associated with adverse cardiovascular and renal outcomes. Careful monitoring and follow-up of patients with AKI in pregnancy may enable earlier detection and management of some adverse cardiovascular and renal outcomes.
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