Evidence map›Paper›PMID 40992930›Full record

SynthesisWorld journal of surgery2025

Bile Duct Replacement in Hepatobiliary Surgery: A Systematic Review.

Mehdi Boubaddi, Chetana Lim, Eric Savier, Claire Goumard, Florence Jeune, Geraldine Rousseau, Filomena Conti, Fabiano Perdigao, Olivier Scatton, Liver Institute of la Pitié‐Salpêtrière (LIPS)

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mehdi BoubaddiAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.ORCID https://orcid.org/0000-0003-2016-6369
Chetana LimAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Eric SavierAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Claire GoumardAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Florence JeuneAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Geraldine RousseauAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Filomena ContiAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service d'Hépatologie, Hôpital Pitié-Salpêtrière, Paris, France.
Fabiano PerdigaoAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Olivier ScattonAssistance Publique, Hôpitaux de Paris, Sorbonne Université, Service de Chirurgie Hépato-biliaire et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France.
Liver Institute of la Pitié‐Salpêtrière (LIPS)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRoux-en-Y hepaticojejunostomy (RYHJ) is currently the standard surgical technique for reestablishing biliary continuity, but it exposes the patient to serious biliary complications, such as anastomosis stricture and ascending cholangitis.

methodsThe literature on biliary replacement using vein grafts as autologous substitutes according to the different stages of the IDEAL framework was reviewed.

resultsInnovative biliary replacement techniques using bile duct substitutes have yet to reach stage 2a (development) of the IDEAL framework. Vein grafts are the most frequently used substitutes in animals and human studies. Twenty-three patients have undergone bile duct reconstruction using four different substitutes: vein grafts (n = 13), omentum/round ligament (n = 5), jejunum (n = 4), and Teflon (n = 1). Biliary replacement using an autologous vein graft (n = 13) was performed for bile duct injury following cholecystectomy (n = 12) or hepatectomy (n = 1). The 90-day mortality rate was zero. Morbidity occurred within 90 days in two patients (15.4%). Twelve patients were alive at the last follow-up.

conclusionsAutologous venous graft as a substitute for biliary replacement may be an appealing alternative to RYHJ in hepatobiliary surgery, but this technique is still being developed.

Indexed as

Bile DuctsAnastomosis, Roux-en-YHepatectomyHumansJejunumOmentumTransplantation, Autologousbiliaryhepaticlivertransplant

Identifiers

PMID40992930
PMCPMC12582139

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.