Evidence map›Paper›PMID 40992542›Full record

ArticleContemporary clinical trials2025

Protocol for a randomized trial of self-management support for people with chronic obstructive pulmonary disease using lay health coaches.

Nikita Agrawal, Meredith Case, Peter K Lindenauer, Danielle McDermott, Keith M Diaz, Jennifer Oscherician Utkin, Juan Wisnivesky, Alex Federman

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06634810 (Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06634810 narecruitingnot on this map

Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2024 to 2027Enrolled300ConditionsChronic Obstructive Pulmonary DiseaseArmsSelf-Management Support, COPD Education
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nikita AgrawalDivision of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, New York, NY, United States of America. Electronic address: Nikita.agrawal@mountsinai.org.
Meredith CaseDivision of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, New York, NY, United States of America; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Peter K LindenauerDepartment of Healthcare Delivery and Population Sciences, University of Massachusetts Chan Medical School - Baystate, Springfield, MA, United States of America.
Danielle McDermottBaystate Medical Center, Springfield, MA, United States of America.
Keith M DiazCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY, United States of America.
Jennifer Oscherician UtkinDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Juan WisniveskyDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Alex FedermanDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.

Funding

Comprehensive Patient-centered Home-based care coaching for COPD self-managementR01HL171695 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Alex D Federman, JUAN P WISNIVESKY · 2024 to 2026
$2.1M
NHLBI NIH HHS R01 HL171695
6 · The paper itself

Abstract

Successful management of chronic obstructive pulmonary disease (COPD) centers on patient self-management behaviors (SMB) such as controller medication adherence, use of action plans, smoking cessation and more. Individuals with COPD face a number of barriers to effective self-management, including medical comorbidities, cognitive and mental health disorders, and socioeconomic factors. Poor self-management contributes significantly to poor health outcomes in patients with COPD. However, prior research has demonstrated that interventions to improve SMB must be multifaceted and tailored to individual patients' specific barriers to be most effective. This randomized control study will test a 6-month self-management support intervention in 300 adults with Global Initiative for Chronic Obstructive Lung Disease (GOLD) classifications B or E. The intervention is called Supporting self-Management Behaviors in Adults with COPD (SAMBA). It uses health coaches to identify and address barriers to SMB, support home-based pulmonary rehabilitation, and promote use of as-needed antibiotics and oral corticosteroids for early treatment of acute COPD exacerbations. SAMBA will be compared to a time and attention matched control treatment consisting of general COPD education. We hypothesize that patients receiving SAMBA will have better COPD medication adherence, greater exercise capacity, more improved COPD symptoms and quality of life, and fewer hospitalizations and ED visits than control patients. CLINICAL TRIAL REGISTRATION NUMBER: NCT06634810.

Indexed as

MentoringPatient Education as TopicPulmonary Disease, Chronic ObstructiveSelf-ManagementAdrenal Cortex HormonesFemaleHumansMaleMedication AdherenceMiddle AgedQuality of LifeRandomized Controlled Trials as TopicAdrenal Cortex HormonesChronic obstructive pulmonary disease (COPD)Health coachesRandomized controlled trialSelf-management support

Identifiers

PMID40992542
PMCPMC13138137

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.