Evidence map›Paper›PMID 40992459›Full record

ArticleVirologica Sinica2025

Long-term surveillance of avian avulavirus in wild birds in China from 2003 to 2020.

Qing An, Yi Li, Xinru Lv, Shunmeng Qu, Xiang Li, Shaoxia Lu, Weiguang Wang, Xuyang Zhao, Yuan Cui, Yang Zhou and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virologica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Qing AnCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Yi LiCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Xinru LvCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Shunmeng QuCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Xiang LiCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Shaoxia LuCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Weiguang WangSchool of Management, Harbin Institute of Technology, Harbin, 150001, China.
Xuyang ZhaoQinghai Wildlife Epidemic Source and Disease Monitoring Station, Xining, 810000, China.
Yuan CuiSanmenxia Affairs Center of Henan Yellow River Wetland National Nature Reserve, Sanmenxia, 472000, China.
Yang ZhouInstitute of Infectious Diseases and Guangzhou Key Laboratory of Clinical Pathogen Research for Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510440, China.
Hongli ZhaiHeilongjiang Ecological Institute, Harbin, 150000, China.
Ao LiCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Fangyuan ChenCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Yang XiuCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Xiangwei ZengCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Yajun WangCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Zhijun HouCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Cheng ChengHeilongjiang International Travel Healthcare Center (Harbin Customs Port Outpatient Department), Harbin, 150000, China. Electronic address: ate_0428@126.com.
Yulong WangCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China. Electronic address: yulongwang73@hotmail.com.
Linna LiuInstitute of Infectious Diseases and Guangzhou Key Laboratory of Clinical Pathogen Research for Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510440, China. Electronic address: liulinna7@126.com.
Hongliang ChaiCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China. Electronic address: Hongliang_Chai@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Avian avulavirus (AAVV) is a significant pathogen affecting avian species, but research on its prevalence in wild birds in China has been relatively limited. In this study, active surveillance for AAVV was conducted in wild birds in China from 2003 to 2020. A total of 124,882 samples were collected from 26 provinces, and 220 AAVV-positive samples were identified, encompassing various serotypes including AAVV-1, -4, -6, -8, -9, -13, and -16. Notably, AAVV-9 isolates were reported for the first time in China through this study. Detailed genetic analysis of 148 representative strains revealed that 26 of them exhibited a polybasic amino acid residue at the F gene cleavage site, a molecular marker associated with virulent AAVV strains in chickens. The geographical isolation between the Old and New Worlds has led to the independent evolution of AAVVs in each region, resulting in distinct Eurasian and North American lineages. Our findings predominantly aligned with the Eurasian lineage. However, repeated detections of AAVVs of North American origin in wild birds in China suggests potential viral dispersal between North America and China, which warrants further investigation. Furthermore, geographical reconstruction of AAVV-4 occurrence indicated a possible transmission route from Europe to East Asia. The origin of AAVV-4 remains uncertain due to limited sequence data, underscoring the need for expanded surveillance and highlight the necessity for sustained, long-term epidemiological surveillance efforts.

Indexed as

Animals, WildAvulavirusAvulavirus InfectionsBird DiseasesBirdsEpidemiological MonitoringAnimalsChinaPhylogenySerogroupAvian avulavirus (AAVV)ChinaNewcastle disease virus (NDV)Viral distributionViral lineagesWild birds

Identifiers

PMID40992459
PMCPMC12665416

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.