Evidence map›Paper›PMID 40991936›Full record

ArticleJMIR research protocols2025

Machine Learning in Health Economic Evaluations: Protocol for a Scoping Review.

Hanan Daghash, Ashleigh Kernohan, Rosiered Brownson-Smith, Rohan Pandey, Ananya Ananthakrishnan, Cen Cong, Victoria Riccalton, Edward Meinert, Gurdeep S Sagoo

Abstract read
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hanan DaghashPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-6966-9955
Ashleigh KernohanPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-5514-3186
Rosiered Brownson-SmithTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-8960-4761
Rohan PandeyPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0009-0003-9494-5792
Ananya AnanthakrishnanTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0009-0000-0292-3923
Cen CongTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0009-0007-8261-6480
Victoria RiccaltonTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0009-0006-5328-6905
Edward MeinertTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-2484-3347
Gurdeep S SagooPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-1427-1437

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, the development of machine learning (ML) applications has increased substantially, indicating the potential role of ML in transforming health care. However, the integration of ML approaches into health economic evaluations is underexplored and has several challenges.

objectiveThis scoping review aims to explore the applications of ML in health economic evaluations. This review will also seek to identify some potential challenges to the use of ML in health economic evaluations.

methodsThis review will use PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) methods. The search will be conducted on MEDLINE (Ovid), Embase (Ovid), IEEE Xplore, and Cochrane Library databases. The eligibility criteria of the selection process will be based on the study types, data sources, methods, and outcomes (SDMO) framework approach.

resultsThe database search yielded 4141 records after removal of retractions and duplicates. Title and abstract screening of 3718 records has been completed, resulting in 30 reports retrieved for eligibility assessment. Data extraction and charting are currently in progress. The results will be published in peer-reviewed journals by the end of 2025.

conclusionsThis review will help to build up the current understanding of how ML applications are integrated in health economics evaluations. This will also explore the potential barriers to and challenges of using ML in health economics evaluations. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/77494.

Indexed as

Economics, MedicalMachine LearningCost-Benefit AnalysisHumansResearch DesignScoping Reviews as Topiccost-effectiveness analysiseconomic evaluationseconomic modellinghealth economicsmachine learning

Identifiers

PMID40991936
PMCPMC12508662

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.