Evidence map›Paper›PMID 40991674›Full record

SynthesisPloS one2025

Exploring risk and protective factors which distinguish suicidal and self-harm behaviours from suicidal and self-harm ideation in young people: A systematic review.

Marianne E Etherson, Sieun Lee, Krystyna J Loney, Isobel P Steward, Joey Ward, Heather McClelland, Aaron Kandola, Josimar A De Alcantara Mendes, Chris Hollis, Ellen Townsend and 3 more

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marianne E EthersonSuicidal Behaviour Research Lab, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-0339-2324
Sieun LeeMental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.ORCID https://orcid.org/0000-0002-9959-6005
Krystyna J LoneySuicidal Behaviour Research Lab, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0009-0005-4900-0751
Isobel P StewardMental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.ORCID https://orcid.org/0000-0002-4534-3352
Joey WardSuicidal Behaviour Research Lab, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Heather McClellandSuicidal Behaviour Research Lab, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0003-2818-5230
Aaron KandolaMRC Unit of Lifelong Health and Ageing, University College London, London, United Kingdom.
Josimar A De Alcantara MendesResponsible Tehcnology Institute, University of Oxford, Oxford, United Kingdom.ORCID https://orcid.org/0000-0001-8230-1998
Chris HollisMental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Ellen TownsendSchool of Psychology, University of Nottingham, Nottingham, United Kingdom.
Dorothee P AuerMental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Rory C O'ConnorSuicidal Behaviour Research Lab, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-3650-4994
Digital Youth Research Programme

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-harm and suicidal thoughts and behaviours among young people are significant global public health concerns. Although most young people with thoughts of self-harm or suicide do not act on their thoughts, it is important to identify factors that distinguish thoughts of self-harm and suicide from behaviours. To date, there are no reviews distinguishing self-harm and suicidal behaviours from thoughts of self-harm and suicide in young people or that have synthesised factors distinguishing self-harm behaviours from self-harm ideation. The current review addresses these gaps in the literature.

methodsWe systematically searched: CINAHL, Embase, Medline, PsycINFO, Psychology and Behavioural Sciences Collection, and Web of Science Core Collection for articles published between 2011 and April 2024. Ninety-nine studies met inclusion criteria, with 92 articles examining risk and protective factors that distinguished suicide attempts from suicidal ideation and seven articles examining factors that distinguished self-harm behaviours from self-harm ideation. Using a narrative synthesis approach, studies were grouped by their outcome variable (e.g., self-harm or suicide) and then by risk and protective factors.

resultsWhile findings were inconsistent, the presence of non-suicidal self-injury, physical, emotional, or sexual abuse, violence, and family factors (e.g., family conflict) distinguished suicidal attempts from suicidal ideation. By contrast, the presence of parental factors (e.g., parental connectedness) and greater academic achievement were protective and distinguished suicidal ideation from suicide attempts. Being female, exposure to self-harm/suicide, and impulsivity distinguished self-harm behaviours from self-harm ideation. There was no evidence of protective factors that distinguished self-harm behaviours from self-harm ideation.

conclusionsThe current review highlights important risk and protective factors that distinguish suicidal and self-harm behaviours from suicidal and self-harm ideation in young people. Our review has important implications for intervention and prevention efforts as identifying key risk and protective factors can improve risk assessment for young people experiencing thoughts of self-harm and suicide and enable more targeted interventions.

Indexed as

Self-Injurious BehaviorSuicidal IdeationSuicideSuicide, AttemptedAdolescentFemaleHumansMaleProtective FactorsRisk FactorsYoung Adult

Identifiers

PMID40991674
PMCPMC12459848

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.