Evidence map›Paper›PMID 40991403›Full record

ArticleZebrafish2025

A Knock-in Zebrafish Reporter Line for Live Visualization of Endogenous Olig2 Protein Dynamics.

Chia-Teng Chang, Toru Kawanishi, Sandy Nandagopal, Sean G Megason, Tony Y-C Tsai

Abstract read
In one paragraph

Article in Zebrafish, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chia-Teng ChangDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, USA.
Toru KawanishiDepartment of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0001-7038-9769
Sandy NandagopalDepartment of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.
Sean G MegasonDepartment of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.
Tony Y-C TsaiDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-1121-9406

Funding

Principles of Mechanochemical Signal Integration Underlying Developmental RobustnessR35GM150759 · NIGMS · WASHINGTON UNIVERSITY · PI Tony Yu-Chen Tsai · 2023 to 2026
$1.5M
The biophysical and genetic basis of robust pattern formation and morphogenesis in zebrafish spinal cordK99HD092623 · NICHD · HARVARD MEDICAL SCHOOL · PI TSAI, TONY YU-CHEN · 2017 to 2018
$256k
Investigating how bHLH circuits integrate signals for cell fate decisionsK99GM151398 · NIGMS · HARVARD MEDICAL SCHOOL · PI NANDAGOPAL, NAGARAJAN · 2023 to 2024
$249k
NICHD NIH HHS K99 HD092623NIGMS NIH HHS K99 GM151398NIGMS NIH HHS R35 GM150759
6 · The paper itself

Abstract

The transcription factor oligodendrocyte transcription factor 2 (Olig2) plays a central role in specifying motor neurons and oligodendrocytes during vertebrate neural development. While transgenic reporter lines such as

Indexed as

Gene Knock-In TechniquesGenes, ReporterOligodendrocyte Transcription Factor 2ZebrafishZebrafish ProteinsAnimalsAnimals, Genetically Modifiedolig2 protein, zebrafishOligodendrocyte Transcription Factor 2Zebrafish ProteinsCRISPR/Cas9knock-inneural progenitorOlig2pMN

Identifiers

PMID40991403
PMCPMC13090830

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.