Evidence map›Paper›PMID 40991343›Full record

ReviewEpileptic disorders : international epilepsy journal with videotape2025

Seminars in epileptology: Presurgical epilepsy evaluation.

Stephan Schuele, Robyn M Busch, Birgit Frauscher, Vadym Gnatkovsky, Hajo Hamer, Lara Jehi, Andres Kanner, Georgia Ramantani, Theodor Rüber, Andreas Schulze-Bonhage and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Epileptic disorders : international epilepsy journal with videotape, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Beyond Broca and Wernicke: Epilepsy surgery in the language areas.Epileptic disorders : international epilepsy journal with videotape · 2026
    Review
  4. Seminars in epileptology: Presurgical epilepsy evaluation.Epileptic disorders : international epilepsy journal with videotape · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stephan SchueleDepartment of Neurology, Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-3261-7120
Robyn M BuschDepartment of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-5442-4912
Birgit FrauscherDepartment of Neurology, Duke University Medical Center and Department of Biomedical Engineering, Duke Pratt School of Engineering, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0001-6064-1529
Vadym GnatkovskyDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-4543-0464
Hajo HamerDepartment of Neurology, Epilepsy Center, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.ORCID https://orcid.org/0000-0003-1709-8617
Lara JehiDepartment of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-8041-6377
Andres KannerDepartment of Neurology, Epilepsy Center, University of Miami, Miami, USA.ORCID https://orcid.org/0000-0003-2857-8034
Georgia RamantaniDepartment of Neuropediatrics, University Children's Hospital Zurich and University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-7931-2327
Theodor RüberDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-6180-7671
Andreas Schulze-BonhageEpilepsy Center, Neurocenter, University Medical Center, University of Freiburg, Freiburg, Germany.ORCID https://orcid.org/0000-0003-2382-0506
Rainer SurgesDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-3177-8582
Lara WadiDepartment of Neurology, Duke University Medical Center, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-2758-9041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All patients with drug-resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic material to create an active working knowledge for the care of patients with focal drug-resistant epilepsy. The article reviews indications for a presurgical evaluation and the importance and benefits of early surgical intervention. Advancements in diagnostic techniques in the presurgical evaluation, including video-EEG monitoring, imaging, neuropsychological testing, and patient selection for invasive monitoring, are covered. An overview of common pathologies underlying surgical epilepsy syndromes and their MRI correlates is provided. A modern multimodal work-up allows individualized risk and benefit estimation and a personalized approach to surgical decision-making. The review concludes with a comprehensive discussion of postsurgical management, common complications, and rehabilitation after epilepsy surgery.

Indexed as

Drug Resistant EpilepsyEpilepsyNeurosurgical ProceduresPreoperative CareElectroencephalographyHumansMagnetic Resonance Imagingetiology of surgical epilepsyfunctional imaginginterictal epileptiform dischargesintracranial electroencephalographynon‐invasive electroencephalographypostoperative carepresurgical evaluationpresurgical neuropsychological assessmentrehabilitationrisk and benefit estimationseizure onset patternstereoelectroencephalographystructural imaging

Identifiers

PMID40991343
PMCPMC12747706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.