ArticleArchives of virology2025
Complete genome sequence and biological characteristics of a novel duck enteritis virus variant with a deletion in UL2.
Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A virulent duck enteritis virus (DEV) isolate, designated DEV JS2024, was obtained from diseased ducks on a routinely vaccinated duck farm in Jiangsu Province. The complete genome sequence of this isolate was determined and found to be 161,600 bp in length. The UL2 of DEV JS2024 is 474 bp in length and was found to be completely identical to that of a commercially available attenuated DEV vaccine (GenBank accession number KF487736). However, it was found to have a continuous 528-bp deletion when compared with the Chinese standard virulent strain (GenBank accession number JQ673560). In addition, there were point mutations in UL32, UL20, UL14, UL7, RS1, and US5. Ducks infected with DEV JS2024 showed characteristic DEV pathology, including clinical manifestations and pathological lesions. The titer of DEV JS2024 in ducks was 10
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