Evidence map›Paper›PMID 40990817›Full record

ReviewInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2025

Gynecologic surgery for benign disease: Preserving reproductive potential.

Togas Tulandi, Edgar Mocanu, Nikhil Purandare, Scott M Nelson, Eytan R Barnea, Ruth Dolmo Carluccio, Elif Goknur Topcu, Dov Feldberg, FIGO Committee on Reproductive Endocrinology and Infertility

Abstract readReview
In one paragraph

Review in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Gynecologic surgery for benign disease: Preserving reproductive potential.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Togas TulandiDepartment of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-5253-2565
Edgar MocanuRotunda Hospital, Dublin, Ireland.
Nikhil PurandareDepartment of Obstetrics and Gynaecology, Galway University Hospital, Galway, Ireland.
Scott M NelsonSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Eytan R BarneaUniversity of Miami Miller School of Medicine, New York, New York, USA.
Ruth Dolmo CarluccioDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA.
Elif Goknur TopcuSisli Kolan International Hospital, Istanbul, Turkey.
Dov FeldbergHelen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, Israel.
FIGO Committee on Reproductive Endocrinology and Infertility

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preserving fertility is essential when managing benign gynecologic disorders in reproductive-aged women. Surgical interventions can impact future fertility, therefore requiring an evidence-based, individualized approach. The FIGO Committee on Reproductive Endocrinology and Infertility reviewed current literature to develop recommendations for fertility-sparing surgical management. Effective treatment must balance disease control with fertility preservation. Evidence supports refined surgical techniques and alternative methods that minimize reproductive harm. In pregnancy loss management, medical treatment is preferred; however, if surgery is needed, hysteroscopic evacuation is safer than sharp curettage, reducing the risk of intrauterine adhesions. Similarly for other operative hysteroscopic procedures or abdominal procedures, including myomectomy, the use of an adhesion-reducing substance is recommended. During abdominal myomectomy, only symptomatic or fertility-impairing fibroids should be removed, as excessive resection may reduce pregnancy chances. In endometrioma surgery, preserving ovarian tissue is crucial by minimizing stripping of the pseudocapsule, or using sclerotherapy may help. Oocyte cryopreservation should be discussed when recurrence or reduced ovarian reserve is a concern. Hydrosalpinx often requires salpingectomy to enhance in vitro fertilization outcomes, but surgeons should protect ovarian blood flow by minimizing thermal injury. For adenomyosis, medical management is preferred due to the risks associated with surgical techniques like the triple-flap procedure. In polycystic ovary syndrome, laparoscopic ovarian drilling is discouraged; ovulation induction with letrozole or gonadotropins is safer and effective. In summary, fertility-sparing treatment demands personalized, evidence-based strategies that prioritize reproductive potential while managing disease. As reproductive goals evolve, continued refinement of these approaches remains vital to women's health care.

Indexed as

Fertility PreservationGenital Diseases, FemaleGynecologic Surgical ProceduresFemaleHumansInfertility, FemaleLeiomyomaPregnancyUterine Myomectomybenign gynecologic surgeryfertility‐sparing surgeryFIGOinfertilityreproductive functionreproductive surgery

Identifiers

PMID40990817
PMCPMC12640173

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.