ArticleBrazilian dental journal2025
Addition of silver nanoparticles to universal adhesive: In vitro effect on biofilm and shear bond strength.
Article in Brazilian dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Novel Metformin-Containing Antibacterial Composite for Root Caries Restorations.Materials (Basel, Switzerland) · 2026Article
- Antibacterial and Bioregenerative Nanomaterials in Oral Health: From Material Design to Clinical Translation and Technological Trends.Journal of functional biomaterials · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silver nanoparticles (AgNPs) have been incorporated into dental materials at low concentrations to provide antibacterial action without compromising mechanical properties. This in vitro study evaluated the antibiofilm effect and bond strength of an experimental universal adhesive with AgNPs (EAg). Streptococcus mutans biofilm was induced by incubating samples with 0.01% and 0.02% AgNPs, based on a pilot study, compared to a control (experimental without AgNPs, ES) in a 20% sucrose medium. This was followed by sonication and counting of viable cells after 1 and 7 days (n = 9). Enamel and dentine bovine micro shear bond strength test (μ-SBS) was performed (n=10) with EAg0.01% and controls (ES and the commercial OPT (Optbond Universal; Kerr). μ-SBS data of enamel and dentin were evaluated for normality and homogeneity by Shapiro-Wilk and Levene, respectively, resulting in normality. Therefore, they were subjected to ANOVA. The failure type was evaluated using a stereoscopic magnifying glass at '40 and categorized as adhesive, cohesive, and mixed failure. The 0.01% concentration demonstrated the antibiofilm effect at the lowest AgNP concentration and was selected for the μ-SBS test. For μ-SBS ANOVA, there were no statistically significant differences between experimental and commercial adhesives (p<0.05). Evaluation of failure mode showed a predominance of adhesive failure on both substrates for all adhesives. The EAg exhibited antibiofilm activity with adhesive performance statistically similar to that of the commercial adhesive. Experimental universal adhesive containing silver nanoparticles showed antibacterial activity without compromising μ-SBS to enamel and dentin.
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Registered trials
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