ReviewMini reviews in medicinal chemistry2025
Antimicrobial Activity of Naturally Occurring and Semi-Synthetic Chlorinated Compounds.
Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION/
objectiveAntimicrobial resistance (AMR) has become a global controversial issue, making conventional treatments less effective. Hence, the design and development of new and efficient antimicrobial agents are on the researchers' agenda to reduce death rates and health care costs. In this regard, chlorine-containing compounds have been the center of attention. This review highlights the antimicrobial potential of chlorine-containing natural and semi-synthetic compounds, aiming to identify versatile candidates effective against microorganisms.
methodsThe literature was comprehensively surveyed using Google Scholar, Web of Science, Scopus, and PubMed, focusing on studies published since 2016, focusing on the antimicrobial properties of natural and semi-synthetic chlorinated compounds.
resultsNatural chlorinated compounds have shown remarkable antimicrobial activity, generally more potent than their semi-synthetic counterparts. DISCUSSION: The strong activity against resistant strains like MRSA underlines their therapeutic potential in addressing pressing clinical challenges. Nature-derived scaffolds serve as a promising foundation for the development of novel antimicrobial agents.
conclusionSeveral naturally occurring compounds have proven more effective than their semisynthetic derivatives, making them attractive candidates for addressing the growing threat of AMR.
Indexed as
Identifiers
40990284What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.