Evidence map›Paper›PMID 40990261›Full record

ArticleNeurourology and urodynamics2026

Impact of Prostatic Urethral Lift and Water Vapor Energy Therapy on Bladder Outlet Obstruction in Elderly or Comorbid Patients With Benign Prostatic Hyperplasia in Real-World Clinical Practice.

Yuki Kyoda, Yoko Saito, Nodoka Kozen, Tetsuya Shindo, Kohei Hashimoto, Ko Kobayashi, Toshiaki Tanaka, Naoya Masumori

Abstract read
In one paragraph

Article in Neurourology and urodynamics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuki KyodaSapporo Medical University School of Medicine, Sapporo, Japan.ORCID https://orcid.org/0000-0003-2046-5051
Yoko SaitoSapporo Medical University School of Medicine, Sapporo, Japan.
Nodoka KozenSapporo Medical University School of Medicine, Sapporo, Japan.
Tetsuya ShindoSapporo Medical University School of Medicine, Sapporo, Japan.ORCID https://orcid.org/0000-0002-4990-8330
Kohei HashimotoSapporo Medical University School of Medicine, Sapporo, Japan.
Ko KobayashiSapporo Medical University School of Medicine, Sapporo, Japan.
Toshiaki TanakaSapporo Medical University School of Medicine, Sapporo, Japan.
Naoya MasumoriSapporo Medical University School of Medicine, Sapporo, Japan.ORCID https://orcid.org/0000-0001-6324-0739

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

objectiveTo evaluate the effects of prostatic urethral lift (PUL) and water vapor energy therapy (WAVE) on bladder outlet obstruction (BOO) using pressure flow studies (PFS) in real-world clinical practice among patients with benign prostatic hyperplasia (BPH), particularly those who are elderly or in poor general health.

methodsThis retrospective study included 128 men who underwent PUL (n = 43), WAVE (n = 38), or photoselective vaporization (PVP, n = 47) for BPH. Surgical procedure selection was based on a department-specific proprietary algorithm. In elderly patients or those with systemic comorbidities, either PUL or WAVE was selected, and the choice between the two procedures was made based on prostate morphology. The primary endpoint was the change in bladder outlet obstruction index (BOOI) from baseline to 6 months after each surgical procedure.

resultsThe BOOI (mean ± SD) significantly decreased from 59.5 ± 26.2 to 14.8 ± 16.7 after PVP, 39.7 ± 21.8 to 25.8 ± 17.7 after PUL, and 52.5 ± 23.9 to 21.9 ± 19.2 after WAVE (all p < 0.01). The International Prostate Symptom Score (IPSS) improved from 17.0 ± 8.8 to 7.0 ± 6.2 (PVP), 16.7 ± 9.0 to 11.5 ± 7.9 (PUL), and 14.7 ± 8.0 to 8.2 ± 6.3 (WAVE) (all p < 0.01). Maximum flow rate (Qmax) increased from 8.6 ± 5.0 to 17.3 ± 7.5 mL/s (PVP), 9.3 ± 5.9 to 12.5 ± 5.8 mL/s (PUL), and 9.2 ± 3.7 to 12.4 ± 6.0 mL/s (WAVE) (all p < 0.01). Despite improvements, residual BOO (Schafer grade ≥ III) remained in 6.4% of PVP, 16.3% of PUL, and 15.8% of WAVE patients.

conclusionIn elderly patients or those with poor general health, both PUL and WAVE significantly improved the BOOI at 6 months postoperatively. However, in PUL and WAVE, persistent BOO exceeded 15%, suggesting that more appropriate patient selection will be necessary in the future.

Indexed as

Laser TherapyProstatic HyperplasiaUrethraUrinary Bladder Neck ObstructionAgedAged, 80 and overComorbidityHumansMaleMiddle AgedRetrospective StudiesSteamTreatment OutcomeUrodynamicsSteambenign prostatic hyperplasiapressure flow studyPULPVPWAVE

Identifiers

PMID40990261
PMCPMC12748029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.