Evidence map›Paper›PMID 40990052›Full record

SynthesisTherapeutic advances in respiratory disease

Differences in genetic characteristics between Chinese and non-Chinese patients with pulmonary alveolar microlithiasis-case series and a systematic review.

Mengyao Guo, Lijuan Hua, Wenxue Bai, Xuezhao Wang, Dongyuan Wang, Lirong Chen, Bingyi Liu, Min Xie

Abstract readSystematic ReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengyao GuoDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.ORCID 0009-0003-0117-0394
Lijuan HuaDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Wenxue BaiDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Xuezhao WangDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Dongyuan WangDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Lirong ChenDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.ORCID 0009-0008-2873-423X
Bingyi LiuDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.ORCID 0000-0002-3006-5564
Min XieDepartment of Emergency and Critical Care Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0003-4052-1647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive disorder caused by

objectivesThis study aims to report three newly identified PAM cases and describe the

designWe documented the diagnosis and treatment processes and genetic variations of three PAM cases for reporting. Furthermore, we searched academic websites for published PAM cases with

methodsWe employed whole-exome sequencing to identify genetic mutations of these three patients. We systematically searched PubMed, Web of Science, China National Knowledge Infrastructure, and Cochrane Library for published PAM cases with

resultsAmong the three cases we reported, two homozygous mutations in

conclusionThis study delineates a distinct spectrum of

Indexed as

CalcinosisEast Asian PeopleGenetic Diseases, InbornLung DiseasesMutationSodium-Phosphate Cotransporter Proteins, Type IIIAdultChinaExome SequencingFemaleGenetic Predisposition to DiseaseHomozygoteHumansMalePhenotypeSodium-Phosphate Cotransporter Proteins, Type IIbSLC34A2 protein, humanSodium-Phosphate Cotransporter Proteins, Type IIbSodium-Phosphate Cotransporter Proteins, Type IIIcase reportChinesegenetic mutationpulmonary alveolar microlithiasis (PAM)SLC34A2 variants

Identifiers

PMID40990052
PMCPMC12461041

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.