ArticleFrontiers in veterinary science2025
Antiseptic susceptibility profiles of canine pyoderma-associated staphylococci in Japan: first identification of plasmid-borne
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: International guidelines recommend the use of antiseptics, such as chlorhexidine, to treat canine pyoderma. However, data on the antiseptic susceptibility of its primary causative agents, Methods: We performed antiseptic susceptibility testing and polymerase chain reaction (PCR) screening for antiseptic resistance-associated genes in these species. In addition, hybrid genome sequencing was conducted for a resistant isolate to investigate the genetic context of resistance genes. Results: Most isolates exhibited low minimum inhibitory concentrations for the tested antiseptics, although some inter-strain variations were observed. One Discussion: These findings highlight the need for continued surveillance of antiseptic resistance-associated genes, which may contribute to reduced phenotypic susceptibility and pose a potential public health concern.
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