Evidence map›Paper›PMID 40989944›Full record

ArticlePlastic and reconstructive surgery. Global open2025

The Role of Urinary Bladder Matrix in Preserving Length and Function After Fingertip Injury.

Meghan C McCullough, Peggy J Ebner, Theodore Brown, Eva Williams, Kylie Tanabe, Haben Berihun, Stuart Kuschner, Vahe Yacoubian, David A Kulber

Abstract read
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Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Meghan C McCulloughFrom the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.
Peggy J EbnerDivision of Plastic and Reconstructive Surgery, University of Southern California, Los Angeles, CA.
Theodore BrownFrom the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.
Eva WilliamsDivision of Plastic and Reconstructive Surgery, University of Southern California, Los Angeles, CA.
Kylie TanabeFrom the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.
Haben BerihunFrom the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.
Stuart KuschnerFrom the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.
Vahe YacoubianTufts School of Medicine, Boston, MA.
David A KulberFrom the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fingertip injuries are an overwhelmingly common but potentially debilitating injury. Preservation of functional length with restoration of sensate, supple tissue is the primary goal of reconstruction. Urinary bladder matrix (UBM) can serve as a tissue regenerator and replacement that can be kept moist with a dual-layer dressing, reducing painful dressing changes to every 10 days. Methods: A retrospective review was performed analyzing all patients treated with UBM for hand and finger injuries at a single institution between 2020 and early 2024. Patient demographics were recorded, including age, sex, level of injury, mechanism of injury, and prior treatments. Surgical outcomes, including time to wound healing, necessity of skin grafting, and postoperative complications, were collected. Results: A total of 23 cases were identified. Mechanisms of injury included traumatic amputation/crush (n = 10), burn injury (n = 1), dog bite (n = 1), ballistic trauma (n = 1), cancer excision (n = 1), septic flexor tenosynovitis requiring debridement (n = 1), and ischemic necrosis (n = 8). All patients underwent surgical debridement followed by application of UBM. Six of 23 patients required secondary skin grafting to achieve full healing. The product was successfully used after preexisting infection in 3 cases. The average time to wound healing was 9.8 weeks (SD 3.4 wk). Conclusions: Fingertip injuries represent a common but challenging reconstructive problem. UBM is a viable alternative to secondary intention healing for fingertip injuries and allows for regeneration of the soft tissue envelope and preservation of length.

Identifiers

PMID40989944
PMCPMC12453368

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.