Evidence map›Paper›PMID 40989938›Full record

ReviewJournal of experimental orthopaedics2025

Limited clinical benefit of medial meniscus posterior root repair combined with high tibial osteotomy in varus knee osteoarthritis: A systematic review and meta-analysis.

Gabriele Cortina, Stefano Mauro Antuofermo, Giuseppe Francesco Papalia, Raffaele Cortina, Vincenzo Condello, Simone Perelli, Joan Carles Monllau, Vincenzo Madonna

Abstract readReview
In one paragraph

Review in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriele CortinaDepartment of Orthopaedic and Trauma Surgery Pierangeli Clinic Pescara Italy.ORCID https://orcid.org/0000-0001-7146-7765
Stefano Mauro AntuofermoOrthopaedic Department University of Sassari Sassari Italy.
Giuseppe Francesco PapaliaOncological Orthopaedics Department IFO - IRCCS Regina Elena National Cancer Institute Rome Italy.ORCID https://orcid.org/0000-0002-4140-738X
Raffaele CortinaDepartment of Orthopaedic and Trauma Surgery Pierangeli Clinic Pescara Italy.
Vincenzo CondelloDepartment of Orthopaedic, Joint Prosthetic, Arthroscopic Surgery and Sports Traumatology Humanitas Castelli Bergamo Italy.
Simone PerelliInstitut Català de Traumatologia i Medicina de l'Esport (ICATME), Hospital Universitari Dexeus Universitat Autònoma de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0003-0010-024X
Joan Carles MonllauInstitut Català de Traumatologia i Medicina de l'Esport (ICATME), Hospital Universitari Dexeus Universitat Autònoma de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0002-2418-4874
Vincenzo MadonnaDepartment of Orthopaedic, Joint Prosthetic, Arthroscopic Surgery and Sports Traumatology Humanitas Castelli Bergamo Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Medial meniscus posterior root tears (MMPRTs) are biomechanically comparable to total meniscectomy, leading to meniscal extrusion, increased tibiofemoral contact pressure and accelerated osteoarthritis (OA) in varus-aligned knees. While high tibial osteotomy (HTO) is effective in unloading the medial compartment, the added value of repairing the MMPRT during HTO remains debated. This systematic review and meta-analysis aimed to evaluate whether combined MMPRT repair and HTO provide superior short-term clinical and radiological outcomes compared to HTO alone. Methods: A systematic search of PubMed, Cochrane and Scopus was performed in March 2025. Comparative studies evaluating HTO with or without concurrent MMPR repair in patients with varus knee and medial OA were included. Primary outcomes were clinical scores (International Knee Documentation Committee [IKDC], Lysholm, Knee Society Score [KSS] and Hospital for Special Surgery [HSS]), radiographic parameters (joint line convergence angle [JLCA], hip-knee-ankle [HKA] angle and joint space width), meniscal extrusion and second-look arthroscopic findings. Statistical analysis was conducted using a random-effects model with Review Manager 5.4. Results: Eight retrospective comparative studies ( Conclusion: Short-term follow-up shows that combining MMPRT repair with HTO yields statistically better IKDC clinical scores. Furthermore, the actual benefit of combining MMPRT repair with HTO in routine clinical practice is questionable. Prospective studies with longer follow-up are required to clarify the long-term clinical impact of MM. Level of Evidence: Level III, systematic review and meta-analysis.

Indexed as

high tibial osteotomy (HTO)medial meniscus posterior root tear (MMPRT)meniscal extrusionmeniscal repairosteoarthritis

Identifiers

PMID40989938
PMCPMC12451467

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.