ReviewBJA open2025
The prognostic value of postoperative cardiac troponin I and T for major adverse cardiac events after coronary artery bypass grafting: a systematic review.
Review in BJA open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This systematic review describes the prognostic value of postoperative cardiac high-sensitive troponin I and T as risk markers for major adverse cardiac events (MACE) after coronary artery bypass graft (CABG) surgery and their predictive performance. Methods: PubMed and Embase were searched up to 14 October 2024. Studies were included if they reported either the association between cardiac troponin I and T and MACE (using risk-, hazard-, or odds ratios) or the accuracy of troponin I and T based prediction models for MACE (using c-statistics and calibration) within 72 h after CABG. MACE was defined as the composite of myocardial infarction, coronary artery revascularisation, cardiac death, non-fatal cardiac arrest, and heart failure. Risk of bias was assessed using the Quality in Prognostic Studies tool. Results: Out of 2273 studies, 10 studies were included. Five studies reported on troponin I (1956 patients) and five on troponin T (5615 patients). MACE composites were heterogenous, with only two studies using an identical composite. Increased postoperative troponin I and T concentrations were associated with higher risk of MACE, with a hazard ratio range of 1.6-11.1 for troponin I ( Conclusions: Postoperative cardiac troponin I and T biomarkers are associated with postoperative MACE after CABG. The current evidence on the predictive value for postoperative MACE is insufficient to use troponin I and T for risk stratification.
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Registered trials
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