ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2025
Use and Outcomes of Medication for Opioid Use Disorder Among Patients With Opioid Use Disorder Undergoing Surgery.
Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Medication for Opioid Use Disorder and Perioperative Outcomes for Benign Hysterectomy.O&G open · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: We examined patterns of use of perioperative medication for opioid use disorder (MOUD) in patients undergoing surgical procedures and assessed the association between MOUD use and perioperative opioid use and postsurgical adverse events. Background: Optimal management of patients with opioid use disorder (OUD) undergoing surgery is unknown. Methods: We identified patients who underwent major and minor surgery from 2016 to 2021 in the MarketScan Database. Patients were classified into OUD and non-OUD groups (opioid-naïve, intermittent use, and chronic use). Among patients with OUD, preoperative MOUD (buprenorphine, methadone) use was noted. Outcomes were compared between patients with and without OUD and among OUD patients who used or did not use MOUD. Results: Of 917,754 surgical patients, 1.6% had OUD, 63.7% were opioid-naïve, 27.8% were intermittent opioid users, and 6.8% were chronic opioid users. Among OUD patients, 27.6% were current MOUD users before surgery. Compared to opioid-naïve patients, patients with OUD had higher rates of persistent perioperative opioid use (42.2% vs. 8.2%), higher rates of emergency department (ED) visits (21.7% vs. 6.9%), and higher rates of readmissions (6.6% vs. 2.2%) within 30 days following surgery (all Conclusions: Among patients with OUD undergoing surgery, preoperative current MOUD is associated with reduced postoperative opioid use, and fewer ED visits and readmissions compared to patients who had a diagnosis of OUD but were untreated.
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