Evidence map›Paper›PMID 40989846›Full record

ArticleFrontiers in pharmacology2025

Safety profile of

Hussin Muhammad, Nik Aina Syazana Nik Zainuddin, Nur Liana Md Nasir, Siti Soleha Ab Dullah, Elda Nurafnie Ibnu Rasid, Mei Siu Lau, Mohd Rahimi Ashraf Abd Rahman, Chin Long Poo, Siti Khadijah Mustapha Kamal, Norizah Awang

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hussin MuhammadToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Nik Aina Syazana Nik ZainuddinToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Nur Liana Md NasirToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Siti Soleha Ab DullahToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Elda Nurafnie Ibnu RasidToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Mei Siu LauToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Mohd Rahimi Ashraf Abd RahmanToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Chin Long PooToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Siti Khadijah Mustapha KamalToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.
Norizah AwangToxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Setia Alam, Selangor, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: An acute oral toxicity study was conducted with single oral doses of 5, 50, 300, and 2000 mg/kg body weight Results: Our findings showed the administration of Discussion:

Indexed as

acute toxicityDioscorea hispidagenotoxicitymicronucleusmutagenicity

Identifiers

PMID40989846
PMCPMC12450958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.