Evidence map›Paper›PMID 40989821›Full record

ArticleFrontiers in pediatrics2025

Reduced exercise capacity in pediatric post-COVID syndrome correlates with time post infection and does not affect quality of life.

Lothar Stein, Svea Mackenrodt, Momme Kück, Sven Haufe, Arno Kerling, Uwe Tegtbur, Valentina Skerries, Martin Wetzke, Christine Happle

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lothar SteinDepartment of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Svea MackenrodtDepartment of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Momme KückDepartment of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Sven HaufeDepartment of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Arno KerlingDepartment of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Uwe TegtburDepartment of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Valentina SkerriesDepartment of Pediatric Pulmology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Martin Wetzke *Department of Pediatric Pulmology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Christine Happle *Department of Pediatric Pulmology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Post-COVID syndrome (PCS) in children and adolescents is reported less frequently and typically of shorter duration than in adults but can be associated with significant morbidity and reduction of quality of life (QoL). In pediatric PCS, data on exercise capacity (EC) are rare. Methods: This prospective, monocentric, cross-sectional study, analyzed EC, QoL, and clinical parameters in pediatric patients with PCS ( Results: The main PCS symptoms were reduced subjective EC (92.4%), shortness of breath (64.2%), concentration difficulties (60.4%), and breathlessness (47.2%). In patients with PCS, EC was 76.6 ± 16.0% VO Conclusion: Pediatric PCS is associated with reduced EC, which is significantly impacted by time post SARS-CoV-2 infection, but does not appear to affect the QoL or self-esteem of the patients in this study.

Indexed as

exercise testingpediatricpost-COVID syndromequality of lifeSARS-CoV-2

Identifiers

PMID40989821
PMCPMC12450661

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.